Estimating the association between antibiotic exposure and colonization with extended-spectrum β-lactamase-producing Gram-negative bacteria using machine learning methods: a multicentre, prospective cohort study

Tacconelli, E.; Górska, A.; De Angelis, G.; Lammens, C.; Restuccia, G.; Schrenzel, Jacques; Huson, D.H.; Carević, B.; Preoţescu, L.; Carmeli, Y.; Kazma, M.; Spanu, T.; Carrara, E.; Malhotra-Kumar, S.; Gladstone, B.P.

doi:10.1016/j.cmi.2019.05.013

Scientific article

English

Estimating the association between antibiotic exposure and colonization with extended-spectrum β-lactamase-producing Gram-negative bacteria using machine learning methods: a multicentre, prospective cohort study

ContributorsTacconelli, E.; Górska, A.; De Angelis, G.; Lammens, C.; Restuccia, G.; Schrenzel, Jacques; Huson, D.H.; Carević, B.; Preoţescu, L.; Carmeli, Y.; Kazma, M.; Spanu, T.; Carrara, E.; Malhotra-Kumar, S.; Gladstone, B.P.

Published inClinical Microbiology and Infection, vol. 26, no. 1, p. 87-94

Publication date2020

Abstract

Objectives: The aim of the study was to measure the impact of antibiotic exposure on the acquisition of colonization with extended-spectrum β-lactamase-producing Gram-negative bacteria (ESBL-GNB) accounting for individual- and group-level confounding using machine-learning methods.

Keywords

Antibiotics usage
Colonization
Extended-spectrum β-lactamase
Incidence rate
Machine learning

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Génomique et microbiote (604)

Funding

European Commission - Impact of Specific Antibiotic Therapies on the prevalence of hUman host ResistaNt bacteria [241796]

Citation (ISO format)

TACCONELLI, E. et al. Estimating the association between antibiotic exposure and colonization with extended-spectrum β-lactamase-producing Gram-negative bacteria using machine learning methods: a multicentre, prospective cohort study. In: Clinical Microbiology and Infection, 2020, vol. 26, n° 1, p. 87–94. doi: 10.1016/j.cmi.2019.05.013

Article (Published version)

Supplemental data

Identifiers

PID : unige:140157
DOI : 10.1016/j.cmi.2019.05.013
PMID : 31128285

Additional URL for this publicationhttps://linkinghub.elsevier.com/retrieve/pii/S1198743X19302472

Journal ISSN1198-743X

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Creation21/07/2020 11:48:00

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Estimating the association between antibiotic exposure and colonization with extended-spectrum β-lactamase-producing Gram-negative bacteria using machine learning methods: a multicentre, prospective cohort study

Objectives: The aim of the study was to measure the impact of antibiotic exposure on the acquisition of colonization with extended-spectrum β-lactamase-producing Gram-negative bacteria (ESBL-GNB) accounting for individual- and group-level confounding using machine-learning methods.

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