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Scientific article
English

Differential sensitivity of human islets from obese versus lean donors to chronic high glucose or palmitate

Published inJournal of Diabetes, vol. 12, no. 7, p. 532-541
Publication date2020
Abstract

Due to the shortage of multi-organ donors, human pancreatic islet transplantation has now been extended to islets originating from obese subjects. In this study, our aim is to compare the respective sensitivity of human islets from lean vs obese donors to chronic high glucose or high palmitate.

Keywords
  • Human islets
  • Insulin secretion
  • Islet transplantation
  • Nitric oxide synthase
  • Obesity
Citation (ISO format)
CASTEX, Françoise et al. Differential sensitivity of human islets from obese versus lean donors to chronic high glucose or palmitate. In: Journal of Diabetes, 2020, vol. 12, n° 7, p. 532–541. doi: 10.1111/1753-0407.13026
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Article (Published version)
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Identifiers
ISSN of the journal1753-0393
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Technical informations

Creation07/08/2020 1:26:00 PM
First validation07/08/2020 1:26:00 PM
Update time03/15/2023 10:17:12 PM
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