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PEDF gene therapy in ovarian cancer

Publication date2019
Abstract

Ovarian cancer-associated ascites is generally considered non-beneficial for disease status. However, our group was able to identify PEDF in the acellular fraction of ascites, which shows antiangiogenic and proapoptotic effects on tumor cells. Thus, we propose inducing PEDF gene expression using the Sleeping Beauty transposon (SBT) system may potentially emerge as a new therapeutic tool in ovarian cancer treatment.

Citation (ISO format)
COHEN, Marie-Benoîte, PETIGNAT, Patrick. PEDF gene therapy in ovarian cancer. In: LEADING OPINIONS. Hämatologie & Onkologie, 2019, vol. 5.
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Article (Published version)
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Identifiers
  • PID : unige:137425
ISSN of the journal1991-2838
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Creation06/18/2020 12:05:00 PM
First validation06/18/2020 12:05:00 PM
Update time03/15/2023 10:10:16 PM
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