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Title

Optimized combinatorial pMHC class II multimer labeling for precision immune monitoring of tumor-specific CD4 T cells in patients

Authors
Rockinger, Georg Alexander
Guillaume, Philippe
Saillard, Margaux
Speiser, Daniel E
Coukos, Georges
Harari, Alexandre
Romero, Pedro J
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Published in Journal for immunotherapy of cancer. 2020, vol. 8, no. 1, p. e000435
Abstract With immunotherapy gaining increasing approval for treatment of different tumor types, scientists rely on cutting edge methods for the monitoring of immune responses and biomarker development in patients. Due to the lack of tools to efficiently detect rare circulating human tumor-specific CD4 T cells, their characterization in patients still remains very limited.
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PMID: 32448802
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Article (Published version) (5.4 MB) - public document Free access
Research group Ciblage des lymphocytes sécrétant des cytokines (1015)
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ROCKINGER, Georg Alexander et al. Optimized combinatorial pMHC class II multimer labeling for precision immune monitoring of tumor-specific CD4 T cells in patients. In: Journal for immunotherapy of cancer, 2020, vol. 8, n° 1, p. e000435. doi: 10.1136/jitc-2019-000435 https://archive-ouverte.unige.ch/unige:137257

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Deposited on : 2020-06-17

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