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Scientific article
English

Nuclear DNA polymorphism in a Mandenka population from Senegal: comparison with eight other human populations

Contributors

Poloni, Estella S.; Excoffier, Laurent Georges Louis; Mountain, J.L.; Langaney, André; Cavalli-Sforza, LL.

Published in

Annals of human genetics, vol. 59, p. 43-61

Publication date

1995

Abstract

A large and ethnically well defined Mandenka sample from Senegal is analysed for 80 nuclear DNA RFLPs, and compared with eight previously studied human populations. A high level of genetic diversity is found in this sample, comparable to that observed in two African Pygmy samples, but lower than that of a European sample. High population variation is observed for most markers. A neutrality test reveals that the markers used in this study can be considered as neutral. A high correlation is found between genetic and geographic distances (r = 0.62), suggesting that geography does also affect long range population genetic relationships and is an important factor behind differentiation among human populations.

Keywords

  • Alleles
  • Cell Nucleus/chemistry
  • Continental Population Groups/genetics
  • DNA/genetics
  • Ethnic Groups/genetics
  • Gene Frequency
  • Genetic Markers
  • Genetic Variation
  • Population Genetics
  • Humans
  • Restriction Fragment Length Polymorphism
  • Senegal

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

POLONI, Estella S. et al. Nuclear DNA polymorphism in a Mandenka population from Senegal: comparison with eight other human populations. In: Annals of human genetics, 1995, vol. 59, p. 43–61. doi: 10.1111/j.1469-1809.1995.tb01605.x

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

0003-4800
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Technical informations

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26/01/2011 12:31:00

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