Scientific article
English

The long and short of fatty acid synthesis

ContributorsRiezman, Howard
Published inCell, vol. 130, no. 4, p. 587-588
Publication date2007
Abstract

The multienzyme complex that synthesizes very long chain fatty acids is embedded in the membrane of the endoplasmic reticulum. In this issue, Denic and Weissman (2007) describe the reconstitution of this complex in liposomes and reveal how elongase proteins (Elops) determine the final length of the fatty acyl CoA chain.

Keywords
  • Acetyltransferases/metabolism
  • Alcohol Oxidoreductases/metabolism
  • Animals
  • Coenzyme A Ligases/metabolism
  • Cytoplasm/metabolism
  • Endoplasmic Reticulum/enzymology
  • Escherichia coli Proteins/isolation & purification/metabolism
  • Fatty Acids, Nonesterified/biosynthesis
  • Humans
  • Hydro-Lyases/metabolism
  • Liposomes/chemistry
  • Models, Biological
  • Oxidoreductases/metabolism
Citation (ISO format)
RIEZMAN, Howard. The long and short of fatty acid synthesis. In: Cell, 2007, vol. 130, n° 4, p. 587–588. doi: 10.1016/j.cell.2007.08.008
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN0092-8674
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Technical informations

Creation06/01/2011 09:19:00
First validation06/01/2011 09:19:00
Update time14/03/2023 16:11:19
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