| Development of Genetically Encoded Fluorescent KSR1-Based Probes to Track Ceramides during Phagocytosis | International journal of molecular sciences | | | 2024 | 153 | 167 |
|
| Alterations of lipid homeostasis in morbid obese patients are partly reversed by bariatric surgery | iScience | | | 2024 | 101 | 107 |
|
| Lysophosphatidylinositols Are Upregulated After Human β-Cell Loss and Potentiate Insulin Release | Diabetes | | | 2024 | 378 | 3 |
|
| Lipid metabolism around the body clocks | Progress in lipid research | | | 2023 | 322 | 857 |
|
| An organelle-specific photoactivation and dual-isotope labeling strategy reveals phosphatidylethanolamine metabolic flux | Chemical science | | | 2023 | 19 | 126 |
|
| Circadian organization of lipid landscape is perturbed in type 2 diabetic patients | Cell reports medicine | | | 2023 | 282 | 162 |
|
| A covalently linked probe to monitor local membrane properties surrounding plasma membrane proteins | The Journal of cell biology | | | 2023 | 19 | 66 |
|
| Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets | PLoS biology | | | 2022 | 315 | 475 |
|
| Plasma membrane effects of sphingolipid-synthesis inhibition by myriocin in CHO cells: a biophysical and lipidomic study | Scientific reports | | | 2022 | 15 | 45 |
|
| Vacuole-Specific Lipid Release for Tracking Intracellular Lipid Metabolism and Transport in Saccharomyces cerevisiae | ACS chemical biology | | | 2022 | 21 | 30 |
|
| CHO/LY‐B cell growth under limiting sphingolipid supply: Correlation between lipid composition and biophysical properties of sphingolipid‐restricted cell membranes | The FASEB journal | | | 2021 | 13 | 77 |
|
| Luciferase Controlled Protein Interactions | Journal of the American Chemical Society | | | 2021 | 344 | 406 |
|
| Genetically Encoded Supramolecular Targeting of Fluorescent Membrane Tension Probes within Live Cells: Precisely Localized Controlled Release by External Chemical Stimulation | JACS Au | | | 2021 | 485 | 532 |
|
| Ether lipids, sphingolipids and toxic 1-deoxyceramides as hallmarks for lean and obese type 2 diabetic patients | Acta Physiologica | | | 2021 | 407 | 3 |
|
| Short Photoswitchable Ceramides Enable Optical Control of Apoptosis | ACS chemical biology | | | 2021 | 13 | 0 |
|
| Flipper Probes for the Community | Chimia | | | 2021 | 475 | 350 |
|
| Determination of the lipid composition of the GPI anchor | PloS one | | | 2021 | 15 | 68 |
|
| Patched regulates lipid homeostasis by controlling cellular cholesterol levels | Nature communications | | | 2021 | 14 | 87 |
|
| HaloFlippers: a General Tool for the Fluorescence Imaging of Precisely Localized Membrane Tension Changes in Living Cells | ACS Central Science | | | 2020 | 452 | 479 |
|
| Combined Omics Approach Identifies Gambogic Acid and Related Xanthones as Covalent Inhibitors of the Serine Palmitoyltransferase Complex | Cell Chemical Biology | | | 2020 | 289 | 0 |
|
| Vesicular and non-vesicular lipid export from the ER to the secretory pathway | Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids | | | 2020 | 399 | 0 |
|
| Conserved Functions of Ether Lipids and Sphingolipids in the Early Secretory Pathway | Current Biology | | | 2020 | 458 | 325 |
|
| Luciferase-Induced Photouncaging: Bioluminolysis | Angewandte Chemie: International Edition | | | 2019 | 524 | 758 |
|
| A Chemogenetic Approach for the Optical Monitoring of Voltage in Neurons | Angewandte Chemie: International Edition | | | 2019 | 311 | 201 |
|
| Yeast ceramide synthases, Lag1 and Lac1, have distinct substrate specificity | Journal of Cell Science | | | 2019 | 371 | 300 |
|
| Lysosome-targeted photoactivation reveals local sphingosine metabolism signatures | Chemical Science | | | 2019 | 523 | 344 |
|
| Optical control of sphingosine-1-phosphate formation and function | Nature chemical biology | | | 2019 | 291 | 0 |
|
| Sphingolipids and membrane targets for therapeutics | Current Opinion in Chemical Biology | | | 2019 | 569 | 3 |
|
| On the road to unraveling the molecular functions of ether lipids | FEBS Letters | | | 2019 | 313 | 0 |
|
| Cytotoxicity of 1-deoxysphingolipid unraveled by genome-wide genetic screens and lipidomics in Saccharomyces cerevisiae | Molecular Biology of the Cell | | | 2019 | 292 | 0 |
|
| Mitochondrial arginase-2 is a cell‑autonomous regulator of CD8+ T cell function and antitumor efficacy | JCI Insight | | | 2019 | 398 | 303 |
|
| Mitochondria-specific photoactivation to monitor local sphingosine metabolism and function | eLife | | | 2018 | 593 | 882 |
|
| Lysophospholipids Facilitate COPII Vesicle Formation | Current Biology | | | 2018 | 322 | 317 |
|
| Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle | eLife | | | 2018 | 599 | 261 |
|
| Understanding the diversity of membrane lipid composition | Nature Reviews Molecular Cell Biology | | | 2018 | 387 | 0 |
|
| Mitochondrial disruption in peroxisome deficient cells is hepatocyte selective but is not mediated by common hepatic peroxisomal metabolites | Mitochondrion | | | 2018 | 311 | 0 |
|
| Structure–function insights into direct lipid transfer between membranes by Mmm1–Mdm12 of ERMES | Journal of Cell Biology | | | 2018 | 409 | 522 |
|
| Macrophages release plasma membrane-derived particles rich in accessible cholesterol | Proceedings of the National Academy of Sciences | | | 2018 | 301 | 0 |
|
| mTORC2 Promotes Tumorigenesis via Lipid Synthesis | Cancer Cell | | | 2017 | 313 | 696 |
|
| Sphingolipid metabolic flow controls phosphoinositide turnover at the trans‐Golgi network | EMBO Journal | | | 2017 | 270 | 0 |
|
| Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency | Journal of Clinical Investigation | | | 2017 | 332 | 217 |
|
| Structure and conserved function of iso-branched sphingoid bases from the nematode Caenorhabditis elegans | Chemical Science | | | 2017 | 274 | 232 |
|
| Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro | Proceedings of the National Academy of Sciences | | | 2017 | 813 | 0 |
|
| Detection of genome-edited mutant clones by a simple competition-based PCR method | PLOS ONE | | | 2017 | 296 | 236 |
|
| Identification and Mode of Action of a Plant Natural Product Targeting Human Fungal Pathogens | Antimicrobial Agents and Chemotherapy | | | 2017 | 595 | 487 |
|
| Membrane Phosphoproteomics of Yeast Early Response to Acetic Acid: Role of Hrk1 Kinase and Lipid Biosynthetic Pathways, in Particular Sphingolipids | Frontiers in Microbiology | | | 2017 | 345 | 269 |
|
| The SAGA complex, together with transcription factors and the endocytic protein Rvs167p, coordinates the reprofiling of gene expression in response to changes in sterol composition in Saccharomyces cerevisiae | Molecular Biology of the Cell | | | 2017 | 514 | 0 |
|
| A method for analysis and design of metabolism using metabolomics data and kinetic models: Application on lipidomics using a novel kinetic model of sphingolipid metabolism | Metabolic Engineering | | | 2016 | 241 | 141 |
|
| Making Sense of the Yeast Sphingolipid Pathway | Journal of Molecular Biology | | | 2016 | 257 | 0 |
|
| Limited ER quality control for GPI-anchored proteins | Journal of Cell Biology | | | 2016 | 206 | 0 |
|
| Trafficking of glycosylphosphatidylinositol anchored proteins from the endoplasmic reticulum to the cell surface | Journal of Lipid Research | | | 2016 | 255 | 0 |
|
| Prolonged starvation drives reversible sequestration of lipid biosynthetic enzymes and organelle reorganization in Saccharomyces cerevisiae | Molecular Biology of the Cell | | | 2015 | 211 | 0 |
|
| Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviour | Nature | | | 2015 | 245 | 1 |
|
| D38-cholesterol as a Raman active probe for imaging intracellular cholesterol storage | Journal of Biomedical Optics | | | 2015 | 259 | 167 |
|
| The SwissLipids knowledgebase for lipid biology | Bioinformatics | | | 2015 | 274 | 266 |
|
| Intracellular sphingosine releases calcium from lysosomes | eLife | | | 2015 | 254 | 141 |
|
| LAPTM4B facilitates late endosomal ceramide export to control cell death pathways | Nature chemical biology | | | 2015 | 213 | 0 |
|
| Autophagy Competes for a Common Phosphatidylethanolamine Pool with Major Cellular PE-Consuming Pathways in Saccharomyces cerevisiae | Genetics | | | 2015 | 208 | 0 |
|
| COPII Coat Composition Is Actively Regulated by Luminal Cargo Maturation | Current Biology | | | 2015 | 215 | 174 |
|
| HCV 3a core protein increases lipid droplet cholesteryl ester content via a mechanism dependent on sphingolipid biosynthesis | PloS one | | | 2014 | 615 | 291 |
|
| A Fluorogenic Probe for SNAP-Tagged Plasma Membrane Proteins Based on the Solvatochromic Molecule Nile Red | ACS Chemical Biology | | | 2014 | 244 | 0 |
|
| Synthetic Multivalent Antifungal Peptides Effective against Fungi | PLOS ONE | | | 2014 | 261 | 245 |
|
| Sphingolipid homeostasis in the web of metabolic routes | Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids | | | 2014 | 265 | 1 |
|
| Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis | Molecular Biology of the Cell | | | 2014 | 568 | 358 |
|
| Lipidomic Profiling of Saccharomyces cerevisiae and Zygosaccharomyces bailii Reveals Critical Changes in Lipid Composition in Response to Acetic Acid Stress | PLOS ONE | | | 2013 | 288 | 457 |
|
| The Peroxisomal Enzyme L-PBE Is Required to Prevent the Dietary Toxicity of Medium-Chain Fatty Acids | Cell Reports | | | 2013 | 289 | 151 |
|
| The Yeast P5 Type ATPase, Spf1, Regulates Manganese Transport into the Endoplasmic Reticulum | PLOS ONE | | | 2013 | 259 | 238 |
|
| TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy | Cell Reports | | | 2013 | 239 | 198 |
|
| Dynamic Amphiphile Libraries To Screen for the "Fragrant" Delivery of siRNA into HeLa Cells and Human Primary Fibroblasts | Journal of the American Chemical Society | | | 2013 | 716 | 497 |
|
| Yeast as a model system for studying lipid homeostasis and function | FEBS Letters | | | 2012 | 363 | 371 |
|
| Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis | Nature cell biology | | | 2012 | 1,084 | 2 |
|
| Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells | Journal of lipid research | | | 2012 | 730 | 548 |
|
| Glycosylphosphatidylinositol anchors regulate glycosphingolipid levels | Journal of Lipid Research | | | 2012 | 401 | 0 |
|
| Amphiphilic dynamic NDI and PDI probes: imaging microdomains in giant unilamellar vesicles | Organic & biomolecular chemistry | | | 2012 | 828 | 427 |
|
| Rsp5 Ubiquitin Ligase Is Required for Protein Trafficking in Saccharomyces cerevisiae COPI Mutants | PLOS ONE | | | 2012 | 265 | 229 |
|
| Loss of ceramide synthase 3 causes lethal skin barrier disruption | Human Molecular Genetics | | | 2012 | 275 | 159 |
|
| Chemical Biology Approaches to Membrane Homeostasis and Function | Chimia | | | 2011 | 836 | 128 |
|
| Mathematical Modeling and Validation of the Ergosterol Pathway in Saccharomyces cerevisiae | PLOS ONE | | | 2011 | 332 | 205 |
|
| Disruption of the ceramide synthase LOH1 causes spontaneous cell death in Arabidopsis thaliana | New Phytologist | | | 2011 | 254 | 0 |
|
| Conceptually New Entries into Cells | Chimia | | | 2011 | 694 | 226 |
|
| NCCR Chemical Biology: Interdisciplinary Research Excellence, Outreach, Education, and New Tools for Switzerland | Chimia | | | 2011 | 237 | 195 |
|
| A Systems Biology Approach Reveals the Role of a Novel Methyltransferase in Response to Chemical Stress and Lipid Homeostasis | PLOS Genetics | | | 2011 | 242 | 117 |
|
| A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance | Metabolic Engineering | | | 2011 | 251 | 1 |
|
| An efficient method for the production of isotopically enriched cholesterol for NMR | Journal of lipid research | | | 2011 | 727 | 0 |
|
| Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI | Journal of Cell Biology | | | 2011 | 204 | 0 |
|
| Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism | Structure | | | 2010 | 235 | 234 |
|
| Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology | Molecular biology of the cell | | | 2009 | 757 | 691 |
|
| Methylation of the Sterol Nucleus by STRM-1 Regulates Dauer Larva Formation in Caenorhabditis elegans | Developmental Cell | | | 2009 | 306 | 0 |
|
| Protection of C. elegans from anoxia by HYL-2 ceramide synthase | Science | | | 2009 | 839 | 985 |
|
| The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular Organization | Chimia | | | 2009 | 268 | 217 |
|
| Concentration of GPI-anchored proteins upon ER exit in yeast | Traffic | | | 2009 | 667 | 0 |
|
| History of Biochemistry at the University of Geneva: From the Boulevard des Philosophes to Quai Ernest-Ansermet | Chimia | | | 2009 | 275 | 197 |
|
| Identifying Key Residues of Sphinganine-1-phosphate Lyase for Function in Vivo and in Vitro | Journal of Biological Chemistry | | | 2008 | 197 | 0 |
|
| The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus | Journal of Cell Biology | | | 2008 | 338 | 114 |
|
| Yeast ARV1 Is Required for Efficient Delivery of an Early GPI Intermediate to the First Mannosyltransferase during GPI Assembly and Controls Lipid Flow from the Endoplasmic Reticulum | Molecular Biology of the Cell | | | 2008 | 215 | 0 |
|
| Natamycin Blocks Fungal Growth by Binding Specifically to Ergosterol without Permeabilizing the Membrane | The Journal of biological chemistry | | | 2008 | 680 | 2 |
|
| Distinct acto/myosin-I structures associate with endocytic profiles at the plasma membrane | Journal of Cell Biology | | | 2008 | 199 | 0 |
|
| Sch9 is a major target of TORC1 in Saccharomyces cerevisiae | Molecular cell | | | 2007 | 687 | 0 |
|
| Proteasome-Independent Functions of Ubiquitin in Endocytosis and Signaling | Science | | | 2007 | 602 | 0 |
|
| The long and short of fatty acid synthesis | Cell | | | 2007 | 648 | 1 |
|
| TEDS Site Phosphorylation of the Yeast Myosins I Is Required for Ligand-induced but Not for Constitutive Endocytosis of the G Protein-coupled Receptor Ste2p | Journal of Biological Chemistry | | | 2006 | 366 | 0 |
|
| Transmembrane topology of ceramide synthase in yeast | Biochemical journal | | | 2006 | 630 | 0 |
|
| Organization and functions of sphingolipid biosynthesis in yeast | Biochemical Society Transactions | | | 2006 | 224 | 0 |
|
| Sphingoid base is required for translation initiation during heat stress in Saccharomyces cerevisiae | Molecular biology of the cell | | | 2006 | 537 | 0 |
|
| Where sterols are required for endocytosis | Biochimica et biophysica acta | | | 2004 | 504 | 0 |
|
| Why Do Cells Require Heat Shock Proteins to Survive Heat Stress? | Cell cycle | | | 2004 | 256 | 0 |
|
| Sorting GPI-anchored proteins | Nature reviews. Molecular cell biology | | | 2004 | 82 | 0 |
|
| Differential ER exit in yeast and mammalian cells | Current Opinion in Cell Biology | | | 2004 | 251 | 0 |
|
| Lipid pickup and delivery | Nature cell biology | | | 2004 | 77 | 0 |
|
| Lcb4p is a key regulator of ceramide synthesis from exogenous long chain sphingoid base in saccharomyces cerevisiae | The Journal of biological chemistry | | | 2003 | 183 | 71 |
|
| Genetic and biochemical interactions between the Arp2/3 complex, Cmd1p, casein kinase II, and Tub4p in yeast | FEMS yeast research | | | 2003 | 505 | 1 |
|
| Drs2p-related P-type ATPases Dnf1p and Dnf2p Are Required for Phospholipid Translocation across the Yeast Plasma Membrane and Serve a Role in Endocytosis | Molecular biology of the cell | | | 2003 | 500 | 0 |
|
| Ordering of Compartments in the Yeast Endocytic Pathway | Traffic | | | 2002 | 75 | 133 |
|
| Biosynthesis and trafficking of sphingolipids in the yeast Saccharomyces cerevisiae | Biochemistry | | | 2002 | 539 | 0 |
|
| Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells | The Journal of biological chemistry | | | 2002 | 139 | 183 |
|
| Sphingolipids are required for the stable membrane association of glycosylphosphatidylinositol-anchored proteins in yeast | The Journal of biological chemistry | | | 2002 | 222 | 211 |
|
| Rho1p mutations specific for regulation of β(1→3)glucan synthesis and the order of assembly of the yeast cell wall | Molecular microbiology | | | 2002 | 61 | 0 |
|
| Identification and characterization of Saccharomyces cerevisiae mutants defective in fluid‐phase endocytosis | Yeast | | | 2001 | 67 | 0 |
|
| Protein Sorting upon Exit from the Endoplasmic Reticulum | Cell | | | 2001 | 524 | 1 |
|
| Rvs161p and Rvs167p, the two yeast amphiphysin homologs, function together in vivo | The Journal of biological chemistry | | | 2001 | 149 | 94 |
|
| Interdependence of filamentous actin and microtubules for asymmetric cell division | Biological chemistry | | | 2000 | 539 | 563 |
|
| Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositol | The Journal of biological chemistry | | | 1999 | 116 | 171 |
|
| Down regulation of yeast G protein-coupled receptors | Seminars in cell & developmental biology | | | 1998 | 78 | 0 |
|
| Actin-, myosin-and ubiquitin-dependent endocytosis | Experientia | | | 1996 | 137 | 223 |
|
