HR
Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
---|---|---|---|---|---|---|---|
Development of Genetically Encoded Fluorescent KSR1-Based Probes to Track Ceramides during Phagocytosis | International journal of molecular sciences | 2024 | 75 | 27 | |||
Alterations of lipid homeostasis in morbid obese patients are partly reversed by bariatric surgery | iScience | 2024 | 32 | 24 | |||
Lysophosphatidylinositols Are Upregulated After Human β-Cell Loss and Potentiate Insulin Release | Diabetes | 2024 | 308 | 2 | |||
Lipid metabolism around the body clocks | Progress in lipid research | 2023 | 247 | 309 | |||
Circadian organization of lipid landscape is perturbed in type 2 diabetic patients | Cell reports. Medicine | 2023 | 215 | 76 | |||
Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets | PLoS biology | 2022 | 240 | 123 | |||
Luciferase Controlled Protein Interactions | Journal of the American Chemical Society | 2021 | 270 | 125 | |||
Genetically Encoded Supramolecular Targeting of Fluorescent Membrane Tension Probes within Live Cells: Precisely Localized Controlled Release by External Chemical Stimulation | JACS Au | 2021 | 400 | 106 | |||
Ether lipids, sphingolipids and toxic 1-deoxyceramides as hallmarks for lean and obese type 2 diabetic patients | Acta Physiologica | 2021 | 337 | 3 | |||
Flipper Probes for the Community | Chimia | 2021 | 379 | 107 | |||
HaloFlippers: a General Tool for the Fluorescence Imaging of Precisely Localized Membrane Tension Changes in Living Cells | ACS Central Science | 2020 | 379 | 233 | |||
Combined Omics Approach Identifies Gambogic Acid and Related Xanthones as Covalent Inhibitors of the Serine Palmitoyltransferase Complex | Cell Chemical Biology | 2020 | 248 | 0 | |||
Vesicular and non-vesicular lipid export from the ER to the secretory pathway | Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids | 2020 | 316 | 0 | |||
Conserved Functions of Ether Lipids and Sphingolipids in the Early Secretory Pathway | Current Biology | 2020 | 401 | 242 | |||
Luciferase-Induced Photouncaging: Bioluminolysis | Angewandte Chemie: International Edition | 2019 | 415 | 363 | |||
A Chemogenetic Approach for the Optical Monitoring of Voltage in Neurons | Angewandte Chemie: International Edition | 2019 | 263 | 166 | |||
Yeast ceramide synthases, Lag1 and Lac1, have distinct substrate specificity | Journal of Cell Science | 2019 | 314 | 144 | |||
Lysosome-targeted photoactivation reveals local sphingosine metabolism signatures | Chemical Science | 2019 | 462 | 170 | |||
Optical control of sphingosine-1-phosphate formation and function | Nature chemical biology | 2019 | 236 | 0 | |||
Sphingolipids and membrane targets for therapeutics | Current Opinion in Chemical Biology | 2019 | 490 | 3 | |||
On the road to unraveling the molecular functions of ether lipids | FEBS Letters | 2019 | 281 | 0 | |||
Cytotoxicity of 1-deoxysphingolipid unraveled by genome-wide genetic screens and lipidomics in Saccharomyces cerevisiae | Molecular Biology of the Cell | 2019 | 245 | 0 | |||
Mitochondrial arginase-2 is a cell‑autonomous regulator of CD8+ T cell function and antitumor efficacy | JCI Insight | 2019 | 345 | 222 | |||
Mitochondria-specific photoactivation to monitor local sphingosine metabolism and function | eLife | 2018 | 531 | 221 | |||
Lysophospholipids Facilitate COPII Vesicle Formation | Current Biology | 2018 | 262 | 152 | |||
Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle | eLife | 2018 | 520 | 190 | |||
Understanding the diversity of membrane lipid composition | Nature Reviews Molecular Cell Biology | 2018 | 301 | 0 | |||
Mitochondrial disruption in peroxisome deficient cells is hepatocyte selective but is not mediated by common hepatic peroxisomal metabolites | Mitochondrion | 2018 | 262 | 0 | |||
Structure–function insights into direct lipid transfer between membranes by Mmm1–Mdm12 of ERMES | Journal of Cell Biology | 2018 | 358 | 319 | |||
Macrophages release plasma membrane-derived particles rich in accessible cholesterol | Proceedings of the National Academy of Sciences | 2018 | 255 | 0 | |||
mTORC2 Promotes Tumorigenesis via Lipid Synthesis | Cancer Cell | 2017 | 267 | 383 | |||
Sphingolipid metabolic flow controls phosphoinositide turnover at the trans‐Golgi network | EMBO Journal | 2017 | 231 | 0 | |||
Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency | Journal of Clinical Investigation | 2017 | 266 | 168 | |||
Structure and conserved function of iso-branched sphingoid bases from the nematode Caenorhabditis elegans | Chemical Science | 2017 | 233 | 112 | |||
Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro | Proceedings of the National Academy of Sciences | 2017 | 766 | 0 | |||
Detection of genome-edited mutant clones by a simple competition-based PCR method | PLOS ONE | 2017 | 253 | 142 | |||
Identification and Mode of Action of a Plant Natural Product Targeting Human Fungal Pathogens | Antimicrobial Agents and Chemotherapy | 2017 | 530 | 230 | |||
Membrane Phosphoproteomics of Yeast Early Response to Acetic Acid: Role of Hrk1 Kinase and Lipid Biosynthetic Pathways, in Particular Sphingolipids | Frontiers in Microbiology | 2017 | 294 | 163 | |||
The SAGA complex, together with transcription factors and the endocytic protein Rvs167p, coordinates the reprofiling of gene expression in response to changes in sterol composition in Saccharomyces cerevisiae | Molecular Biology of the Cell | 2017 | 478 | 0 | |||
A method for analysis and design of metabolism using metabolomics data and kinetic models: Application on lipidomics using a novel kinetic model of sphingolipid metabolism | Metabolic Engineering | 2016 | 196 | 92 | |||
Making Sense of the Yeast Sphingolipid Pathway | Journal of Molecular Biology | 2016 | 202 | 0 | |||
Limited ER quality control for GPI-anchored proteins | Journal of Cell Biology | 2016 | 175 | 0 | |||
Trafficking of glycosylphosphatidylinositol anchored proteins from the endoplasmic reticulum to the cell surface | Journal of Lipid Research | 2016 | 214 | 0 | |||
Prolonged starvation drives reversible sequestration of lipid biosynthetic enzymes and organelle reorganization in Saccharomyces cerevisiae | Molecular Biology of the Cell | 2015 | 165 | 0 | |||
Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviour | Nature | 2015 | 194 | 1 | |||
D38-cholesterol as a Raman active probe for imaging intracellular cholesterol storage | Journal of Biomedical Optics | 2015 | 202 | 135 | |||
The SwissLipids knowledgebase for lipid biology | Bioinformatics | 2015 | 222 | 91 | |||
Intracellular sphingosine releases calcium from lysosomes | eLife | 2015 | 211 | 114 | |||
LAPTM4B facilitates late endosomal ceramide export to control cell death pathways | Nature chemical biology | 2015 | 177 | 0 | |||
Autophagy Competes for a Common Phosphatidylethanolamine Pool with Major Cellular PE-Consuming Pathways in Saccharomyces cerevisiae | Genetics | 2015 | 178 | 0 | |||
COPII Coat Composition Is Actively Regulated by Luminal Cargo Maturation | Current Biology | 2015 | 180 | 117 | |||
HCV 3a core protein increases lipid droplet cholesteryl ester content via a mechanism dependent on sphingolipid biosynthesis | PloS one | 2014 | 560 | 214 | |||
A Fluorogenic Probe for SNAP-Tagged Plasma Membrane Proteins Based on the Solvatochromic Molecule Nile Red | ACS Chemical Biology | 2014 | 212 | 0 | |||
Synthetic Multivalent Antifungal Peptides Effective against Fungi | PLOS ONE | 2014 | 210 | 119 | |||
Sphingolipid homeostasis in the web of metabolic routes | Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids | 2014 | 230 | 1 | |||
Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis | Molecular Biology of the Cell | 2014 | 533 | 250 | |||
Lipidomic Profiling of Saccharomyces cerevisiae and Zygosaccharomyces bailii Reveals Critical Changes in Lipid Composition in Response to Acetic Acid Stress | PLOS ONE | 2013 | 232 | 93 | |||
The Peroxisomal Enzyme L-PBE Is Required to Prevent the Dietary Toxicity of Medium-Chain Fatty Acids | Cell Reports | 2013 | 234 | 89 | |||
The Yeast P5 Type ATPase, Spf1, Regulates Manganese Transport into the Endoplasmic Reticulum | PLOS ONE | 2013 | 198 | 133 | |||
TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy | Cell Reports | 2013 | 186 | 117 | |||
Dynamic Amphiphile Libraries To Screen for the "Fragrant" Delivery of siRNA into HeLa Cells and Human Primary Fibroblasts | Journal of the American Chemical Society | 2013 | 660 | 314 | |||
Yeast as a model system for studying lipid homeostasis and function | FEBS Letters | 2012 | 316 | 159 | |||
Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis | Nature cell biology | 2012 | 1,041 | 2 | |||
Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells | Journal of lipid research | 2012 | 692 | 501 | |||
Glycosylphosphatidylinositol anchors regulate glycosphingolipid levels | Journal of Lipid Research | 2012 | 360 | 0 | |||
Amphiphilic dynamic NDI and PDI probes: imaging microdomains in giant unilamellar vesicles | Organic & biomolecular chemistry | 2012 | 763 | 251 | |||
Rsp5 Ubiquitin Ligase Is Required for Protein Trafficking in Saccharomyces cerevisiae COPI Mutants | PLOS ONE | 2012 | 227 | 112 | |||
Loss of ceramide synthase 3 causes lethal skin barrier disruption | Human Molecular Genetics | 2012 | 236 | 118 | |||
Chemical Biology Approaches to Membrane Homeostasis and Function | Chimia | 2011 | 750 | 60 | |||
Mathematical Modeling and Validation of the Ergosterol Pathway in Saccharomyces cerevisiae | PLOS ONE | 2011 | 281 | 100 | |||
Disruption of the ceramide synthase LOH1 causes spontaneous cell death in Arabidopsis thaliana | New Phytologist | 2011 | 197 | 0 | |||
Conceptually New Entries into Cells | Chimia | 2011 | 634 | 124 | |||
NCCR Chemical Biology: Interdisciplinary Research Excellence, Outreach, Education, and New Tools for Switzerland | Chimia | 2011 | 194 | 123 | |||
A Systems Biology Approach Reveals the Role of a Novel Methyltransferase in Response to Chemical Stress and Lipid Homeostasis | PLOS Genetics | 2011 | 196 | 52 | |||
A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance | Metabolic Engineering | 2011 | 203 | 1 | |||
An efficient method for the production of isotopically enriched cholesterol for NMR | Journal of lipid research | 2011 | 654 | 0 | |||
Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI | Journal of Cell Biology | 2011 | 173 | 0 | |||
Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism | Structure | 2010 | 182 | 109 | |||
Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology | Molecular biology of the cell | 2009 | 686 | 519 | |||
Methylation of the Sterol Nucleus by STRM-1 Regulates Dauer Larva Formation in Caenorhabditis elegans | Developmental Cell | 2009 | 218 | 0 | |||
Protection of C. elegans from anoxia by HYL-2 ceramide synthase | Science | 2009 | 774 | 705 | |||
The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular Organization | Chimia | 2009 | 218 | 127 | |||
Concentration of GPI-anchored proteins upon ER exit in yeast | Traffic | 2009 | 612 | 0 | |||
History of Biochemistry at the University of Geneva: From the Boulevard des Philosophes to Quai Ernest-Ansermet | Chimia | 2009 | 224 | 114 | |||
Identifying Key Residues of Sphinganine-1-phosphate Lyase for Function in Vivo and in Vitro | Journal of Biological Chemistry | 2008 | 161 | 0 | |||
The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus | Journal of Cell Biology | 2008 | 293 | 67 | |||
Yeast ARV1 Is Required for Efficient Delivery of an Early GPI Intermediate to the First Mannosyltransferase during GPI Assembly and Controls Lipid Flow from the Endoplasmic Reticulum | Molecular Biology of the Cell | 2008 | 164 | 0 | |||
Natamycin Blocks Fungal Growth by Binding Specifically to Ergosterol without Permeabilizing the Membrane | The Journal of biological chemistry | 2008 | 594 | 2 | |||
Distinct acto/myosin-I structures associate with endocytic profiles at the plasma membrane | Journal of Cell Biology | 2008 | 157 | 0 | |||
Sch9 is a major target of TORC1 in Saccharomyces cerevisiae | Molecular cell | 2007 | 638 | 0 | |||
Proteasome-Independent Functions of Ubiquitin in Endocytosis and Signaling | Science | 2007 | 549 | 0 | |||
The long and short of fatty acid synthesis | Cell | 2007 | 590 | 1 | |||
TEDS Site Phosphorylation of the Yeast Myosins I Is Required for Ligand-induced but Not for Constitutive Endocytosis of the G Protein-coupled Receptor Ste2p | Journal of Biological Chemistry | 2006 | 316 | 0 | |||
Transmembrane topology of ceramide synthase in yeast | Biochemical journal | 2006 | 593 | 0 | |||
Organization and functions of sphingolipid biosynthesis in yeast | Biochemical Society Transactions | 2006 | 180 | 0 | |||
Sphingoid base is required for translation initiation during heat stress in Saccharomyces cerevisiae | Molecular biology of the cell | 2006 | 487 | 0 | |||
Where sterols are required for endocytosis | Biochimica et biophysica acta | 2004 | 455 | 0 | |||
Why Do Cells Require Heat Shock Proteins to Survive Heat Stress? | Cell cycle | 2004 | 195 | 0 | |||
Sorting GPI-anchored proteins | Nature reviews. Molecular cell biology | 2004 | 48 | 0 | |||
Differential ER exit in yeast and mammalian cells | Current Opinion in Cell Biology | 2004 | 208 | 0 | |||
Lipid pickup and delivery | Nature cell biology | 2004 | 44 | 0 | |||
Lcb4p is a key regulator of ceramide synthesis from exogenous long chain sphingoid base in saccharomyces cerevisiae | The Journal of biological chemistry | 2003 | 141 | 30 | |||
Genetic and biochemical interactions between the Arp2/3 complex, Cmd1p, casein kinase II, and Tub4p in yeast | FEMS yeast research | 2003 | 465 | 1 | |||
Drs2p-related P-type ATPases Dnf1p and Dnf2p Are Required for Phospholipid Translocation across the Yeast Plasma Membrane and Serve a Role in Endocytosis | Molecular biology of the cell | 2003 | 451 | 0 | |||
Ordering of Compartments in the Yeast Endocytic Pathway | Traffic | 2002 | 36 | 26 | |||
Biosynthesis and trafficking of sphingolipids in the yeast Saccharomyces cerevisiae | Biochemistry | 2002 | 503 | 0 | |||
Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells | The Journal of biological chemistry | 2002 | 76 | 86 | |||
Sphingolipids are required for the stable membrane association of glycosylphosphatidylinositol-anchored proteins in yeast | The Journal of biological chemistry | 2002 | 161 | 84 | |||
Rho1p mutations specific for regulation of β(1→3)glucan synthesis and the order of assembly of the yeast cell wall | Molecular microbiology | 2002 | 35 | 0 | |||
Identification and characterization of Saccharomyces cerevisiae mutants defective in fluid‐phase endocytosis | Yeast | 2001 | 29 | 0 | |||
Protein Sorting upon Exit from the Endoplasmic Reticulum | Cell | 2001 | 478 | 1 | |||
Rvs161p and Rvs167p, the two yeast amphiphysin homologs, function together in vivo | The Journal of biological chemistry | 2001 | 112 | 25 | |||
Interdependence of filamentous actin and microtubules for asymmetric cell division | Biological chemistry | 2000 | 490 | 362 | |||
Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositol | The Journal of biological chemistry | 1999 | 73 | 75 | |||
Down regulation of yeast G protein-coupled receptors | Seminars in cell & developmental biology | 1998 | 50 | 0 | |||
Actin-, myosin-and ubiquitin-dependent endocytosis | Experientia | 1996 | 96 | 81 |