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Development of Genetically Encoded Fluorescent KSR1-Based Probes to Track Ceramides during PhagocytosisInternational journal of molecular sciences
accessLevelPublic
2024 15 2
Lysophosphatidylinositols Are Upregulated After Human β-Cell Loss and Potentiate Insulin ReleaseDiabetes
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2024 207 1
Lipid metabolism around the body clocksProgress in lipid research
accessLevelPublic
2023 181 166
Circadian organization of lipid landscape is perturbed in type 2 diabetic patientsCell reports. Medicine
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2023 133 43
Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic isletsPLoS biology
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2022 188 104
Luciferase Controlled Protein InteractionsJournal of the American Chemical Society
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2021 228 50
Genetically Encoded Supramolecular Targeting of Fluorescent Membrane Tension Probes within Live Cells: Precisely Localized Controlled Release by External Chemical StimulationJACS Au
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2021 355 87
Ether lipids, sphingolipids and toxic 1-deoxyceramides as hallmarks for lean and obese type 2 diabetic patientsActa Physiologica
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2021 283 3
Flipper Probes for the CommunityChimia
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2021 326 75
HaloFlippers: a General Tool for the Fluorescence Imaging of Precisely Localized Membrane Tension Changes in Living CellsACS Central Science
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2020 335 198
Combined Omics Approach Identifies Gambogic Acid and Related Xanthones as Covalent Inhibitors of the Serine Palmitoyltransferase ComplexCell Chemical Biology
accessLevelRestricted
2020 222 0
Vesicular and non-vesicular lipid export from the ER to the secretory pathwayBiochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
accessLevelRestricted
2020 277 0
Conserved Functions of Ether Lipids and Sphingolipids in the Early Secretory PathwayCurrent Biology
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2020 350 224
Luciferase-Induced Photouncaging: BioluminolysisAngewandte Chemie: International Edition
accessLevelPublic
2019 365 261
A Chemogenetic Approach for the Optical Monitoring of Voltage in NeuronsAngewandte Chemie: International Edition
accessLevelPublic
2019 240 158
Yeast ceramide synthases, Lag1 and Lac1, have distinct substrate specificityJournal of Cell Science
accessLevelPublic
2019 281 110
Lysosome-targeted photoactivation reveals local sphingosine metabolism signaturesChemical Science
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2019 440 155
Optical control of sphingosine-1-phosphate formation and functionNature chemical biology
accessLevelRestricted
2019 224 0
Sphingolipids and membrane targets for therapeuticsCurrent Opinion in Chemical Biology
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2019 461 3
On the road to unraveling the molecular functions of ether lipidsFEBS Letters
accessLevelRestricted
2019 254 0
Cytotoxicity of 1-deoxysphingolipid unraveled by genome-wide genetic screens and lipidomics in Saccharomyces cerevisiaeMolecular Biology of the Cell
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2019 225 0
Mitochondrial arginase-2 is a cell‑autonomous regulator of CD8+ T cell function and antitumor efficacyJCI Insight
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2019 311 199
Mitochondria-specific photoactivation to monitor local sphingosine metabolism and functioneLife
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2018 492 200
Lysophospholipids Facilitate COPII Vesicle FormationCurrent Biology
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2018 231 133
Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscleeLife
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2018 474 183
Understanding the diversity of membrane lipid compositionNature Reviews Molecular Cell Biology
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2018 272 0
Mitochondrial disruption in peroxisome deficient cells is hepatocyte selective but is not mediated by common hepatic peroxisomal metabolitesMitochondrion
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2018 242 0
Structure–function insights into direct lipid transfer between membranes by Mmm1–Mdm12 of ERMESJournal of Cell Biology
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2018 339 300
Macrophages release plasma membrane-derived particles rich in accessible cholesterolProceedings of the National Academy of Sciences
accessLevelRestricted
2018 241 0
mTORC2 Promotes Tumorigenesis via Lipid SynthesisCancer Cell
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2017 251 300
Sphingolipid metabolic flow controls phosphoinositide turnover at the trans‐Golgi networkEMBO Journal
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2017 211 0
Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiencyJournal of Clinical Investigation
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2017 232 145
Structure and conserved function of iso-branched sphingoid bases from the nematode Caenorhabditis elegansChemical Science
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2017 208 95
Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitroProceedings of the National Academy of Sciences
accessLevelRestricted
2017 726 0
Detection of genome-edited mutant clones by a simple competition-based PCR methodPLOS ONE
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2017 231 127
Identification and Mode of Action of a Plant Natural Product Targeting Human Fungal PathogensAntimicrobial Agents and Chemotherapy
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2017 503 214
Membrane Phosphoproteomics of Yeast Early Response to Acetic Acid: Role of Hrk1 Kinase and Lipid Biosynthetic Pathways, in Particular SphingolipidsFrontiers in Microbiology
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2017 270 150
The SAGA complex, together with transcription factors and the endocytic protein Rvs167p, coordinates the reprofiling of gene expression in response to changes in sterol composition in Saccharomyces cerevisiaeMolecular Biology of the Cell
accessLevelRestricted
2017 442 0
A method for analysis and design of metabolism using metabolomics data and kinetic models: Application on lipidomics using a novel kinetic model of sphingolipid metabolismMetabolic Engineering
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2016 174 78
Making Sense of the Yeast Sphingolipid PathwayJournal of Molecular Biology
accessLevelRestricted
2016 181 0
Limited ER quality control for GPI-anchored proteinsJournal of Cell Biology
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2016 158 0
Trafficking of glycosylphosphatidylinositol anchored proteins from the endoplasmic reticulum to the cell surfaceJournal of Lipid Research
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2016 202 0
Prolonged starvation drives reversible sequestration of lipid biosynthetic enzymes and organelle reorganization in Saccharomyces cerevisiaeMolecular Biology of the Cell
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2015 153 0
Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviourNature
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2015 175 1
D38-cholesterol as a Raman active probe for imaging intracellular cholesterol storageJournal of Biomedical Optics
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2015 178 126
The SwissLipids knowledgebase for lipid biologyBioinformatics
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2015 198 79
Intracellular sphingosine releases calcium from lysosomeseLife
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2015 195 109
LAPTM4B facilitates late endosomal ceramide export to control cell death pathwaysNature chemical biology
accessLevelRestricted
2015 165 0
Autophagy Competes for a Common Phosphatidylethanolamine Pool with Major Cellular PE-Consuming Pathways in Saccharomyces cerevisiaeGenetics
accessLevelRestricted
2015 157 0
COPII Coat Composition Is Actively Regulated by Luminal Cargo MaturationCurrent Biology
accessLevelPublic
2015 167 101
HCV 3a core protein increases lipid droplet cholesteryl ester content via a mechanism dependent on sphingolipid biosynthesisPloS one
accessLevelPublic
2014 535 203
A Fluorogenic Probe for SNAP-Tagged Plasma Membrane Proteins Based on the Solvatochromic Molecule Nile RedACS Chemical Biology
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2014 199 0
Synthetic Multivalent Antifungal Peptides Effective against FungiPLOS ONE
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2014 188 114
Sphingolipid homeostasis in the web of metabolic routesBiochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
accessLevelRestricted
2014 216 1
Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasisMolecular Biology of the Cell
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2014 501 240
Lipidomic Profiling of Saccharomyces cerevisiae and Zygosaccharomyces bailii Reveals Critical Changes in Lipid Composition in Response to Acetic Acid StressPLOS ONE
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2013 210 72
The Peroxisomal Enzyme L-PBE Is Required to Prevent the Dietary Toxicity of Medium-Chain Fatty AcidsCell Reports
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2013 213 80
The Yeast P5 Type ATPase, Spf1, Regulates Manganese Transport into the Endoplasmic ReticulumPLOS ONE
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2013 182 110
TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and AutophagyCell Reports
accessLevelPublic
2013 170 97
Dynamic Amphiphile Libraries To Screen for the "Fragrant" Delivery of siRNA into HeLa Cells and Human Primary FibroblastsJournal of the American Chemical Society
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2013 634 273
Yeast as a model system for studying lipid homeostasis and functionFEBS Letters
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2012 295 137
Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesisNature cell biology
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2012 1 013 2
Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cellsJournal of lipid research
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2012 673 484
Glycosylphosphatidylinositol anchors regulate glycosphingolipid levelsJournal of Lipid Research
accessLevelRestricted
2012 342 0
Amphiphilic dynamic NDI and PDI probes: imaging microdomains in giant unilamellar vesiclesOrganic & biomolecular chemistry
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2012 721 159
Rsp5 Ubiquitin Ligase Is Required for Protein Trafficking in Saccharomyces cerevisiae COPI MutantsPLOS ONE
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2012 208 109
Loss of ceramide synthase 3 causes lethal skin barrier disruptionHuman Molecular Genetics
accessLevelPublic
2012 224 108
Chemical Biology Approaches to Membrane Homeostasis and FunctionChimia
accessLevelPublic
2011 689 51
Mathematical Modeling and Validation of the Ergosterol Pathway in Saccharomyces cerevisiaePLOS ONE
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2011 258 85
Disruption of the ceramide synthase LOH1 causes spontaneous cell death in Arabidopsis thalianaNew Phytologist
accessLevelRestricted
2011 173 0
Conceptually New Entries into CellsChimia
accessLevelPublic
2011 606 110
NCCR Chemical Biology: Interdisciplinary Research Excellence, Outreach, Education, and New Tools for SwitzerlandChimia
accessLevelPublic
2011 177 115
A Systems Biology Approach Reveals the Role of a Novel Methyltransferase in Response to Chemical Stress and Lipid HomeostasisPLOS Genetics
accessLevelPublic
2011 156 44
A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistanceMetabolic Engineering
accessLevelRestricted
2011 181 1
An efficient method for the production of isotopically enriched cholesterol for NMRJournal of lipid research
accessLevelRestricted
2011 632 0
Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPIJournal of Cell Biology
accessLevelRestricted
2011 158 0
Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid MetabolismStructure
accessLevelPublic
2010 157 74
Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiologyMolecular biology of the cell
accessLevelPublic
2009 654 479
Methylation of the Sterol Nucleus by STRM-1 Regulates Dauer Larva Formation in Caenorhabditis elegansDevelopmental Cell
accessLevelRestricted
2009 187 0
Protection of C. elegans from anoxia by HYL-2 ceramide synthaseScience
accessLevelPublic
2009 749 632
The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular OrganizationChimia
accessLevelPublic
2009 184 108
Concentration of GPI-anchored proteins upon ER exit in yeastTraffic
accessLevelRestricted
2009 595 0
History of Biochemistry at the University of Geneva: From the Boulevard des Philosophes to Quai Ernest-AnsermetChimia
accessLevelPublic
2009 201 106
Identifying Key Residues of Sphinganine-1-phosphate Lyase for Function in Vivo and in VitroJournal of Biological Chemistry
accessLevelRestricted
2008 145 0
The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatusJournal of Cell Biology
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2008 277 59
Yeast ARV1 Is Required for Efficient Delivery of an Early GPI Intermediate to the First Mannosyltransferase during GPI Assembly and Controls Lipid Flow from the Endoplasmic ReticulumMolecular Biology of the Cell
accessLevelRestricted
2008 142 0
Natamycin Blocks Fungal Growth by Binding Specifically to Ergosterol without Permeabilizing the MembraneThe Journal of biological chemistry
accessLevelRestricted
2008 566 2
Distinct acto/myosin-I structures associate with endocytic profiles at the plasma membraneJournal of Cell Biology
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2008 142 0
Sch9 is a major target of TORC1 in Saccharomyces cerevisiaeMolecular cell
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2007 602 0
Proteasome-Independent Functions of Ubiquitin in Endocytosis and SignalingScience
accessLevelRestricted
2007 526 0
The long and short of fatty acid synthesisCell
accessLevelRestricted
2007 561 1
TEDS Site Phosphorylation of the Yeast Myosins I Is Required for Ligand-induced but Not for Constitutive Endocytosis of the G Protein-coupled Receptor Ste2pJournal of Biological Chemistry
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2006 302 0
Transmembrane topology of ceramide synthase in yeastBiochemical journal
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2006 577 0
Organization and functions of sphingolipid biosynthesis in yeastBiochemical Society Transactions
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2006 162 0
Sphingoid base is required for translation initiation during heat stress in Saccharomyces cerevisiaeMolecular biology of the cell
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2006 461 0
Where sterols are required for endocytosisBiochimica et biophysica acta
accessLevelRestricted
2004 437 0
Why Do Cells Require Heat Shock Proteins to Survive Heat Stress?Cell cycle
accessLevelRestricted
2004 174 0
Sorting GPI-anchored proteinsNature reviews. Molecular cell biology
accessLevelRestricted
2004 25 0
Differential ER exit in yeast and mammalian cellsCurrent Opinion in Cell Biology
accessLevelRestricted
2004 186 0
Lipid pickup and deliveryNature cell biology
accessLevelRestricted
2004 27 0
Lcb4p is a key regulator of ceramide synthesis from exogenous long chain sphingoid base in saccharomyces cerevisiaeThe Journal of biological chemistry
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2003 109 23
Genetic and biochemical interactions between the Arp2/3 complex, Cmd1p, casein kinase II, and Tub4p in yeastFEMS yeast research
accessLevelRestricted
2003 450 1
Drs2p-related P-type ATPases Dnf1p and Dnf2p Are Required for Phospholipid Translocation across the Yeast Plasma Membrane and Serve a Role in EndocytosisMolecular biology of the cell
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2003 417 0
Ordering of Compartments in the Yeast Endocytic PathwayTraffic
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2002 21 5
Biosynthesis and trafficking of sphingolipids in the yeast Saccharomyces cerevisiaeBiochemistry
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2002 489 0
Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cellsThe Journal of biological chemistry
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2002 53 56
Sphingolipids are required for the stable membrane association of glycosylphosphatidylinositol-anchored proteins in yeastThe Journal of biological chemistry
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2002 135 55
Rho1p mutations specific for regulation of β(1→3)glucan synthesis and the order of assembly of the yeast cell wallMolecular microbiology
accessLevelRestricted
2002 22 0
Identification and characterization of Saccharomyces cerevisiae mutants defective in fluid‐phase endocytosisYeast
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2001 15 0
Protein Sorting upon Exit from the Endoplasmic ReticulumCell
accessLevelRestricted
2001 458 1
Rvs161p and Rvs167p, the two yeast amphiphysin homologs, function together in vivoThe Journal of biological chemistry
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2001 98 15
Interdependence of filamentous actin and microtubules for asymmetric cell divisionBiological chemistry
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2000 463 323
Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositolThe Journal of biological chemistry
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1999 51 48
Down regulation of yeast G protein-coupled receptorsSeminars in cell & developmental biology
accessLevelRestricted
1998 30 0
Actin-, myosin-and ubiquitin-dependent endocytosisExperientia
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1996 82 64
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