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Development of Genetically Encoded Fluorescent KSR1-Based Probes to Track Ceramides during PhagocytosisInternational journal of molecular sciences
accessLevelPublic
2024 140 95
Alterations of lipid homeostasis in morbid obese patients are partly reversed by bariatric surgeryiScience
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2024 87 62
Lysophosphatidylinositols Are Upregulated After Human β-Cell Loss and Potentiate Insulin ReleaseDiabetes
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2024 366 3
Lipid metabolism around the body clocksProgress in lipid research
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2023 309 547
An organelle-specific photoactivation and dual-isotope labeling strategy reveals phosphatidylethanolamine metabolic fluxChemical science
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2023 8 23
Circadian organization of lipid landscape is perturbed in type 2 diabetic patientsCell reports. Medicine
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2023 270 139
A covalently linked probe to monitor local membrane properties surrounding plasma membrane proteinsThe Journal of cell biology
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2023 10 14
Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic isletsPLoS biology
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2022 300 238
Plasma membrane effects of sphingolipid-synthesis inhibition by myriocin in CHO cells: a biophysical and lipidomic studyScientific reports
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2022 5 12
Vacuole-Specific Lipid Release for Tracking Intracellular Lipid Metabolism and Transport in Saccharomyces cerevisiae ACS chemical biology
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2022 9 9
CHO/LY‐B cell growth under limiting sphingolipid supply: Correlation between lipid composition and biophysical properties of sphingolipid‐restricted cell membranesThe FASEB journal
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2021 5 8
Luciferase Controlled Protein InteractionsJournal of the American Chemical Society
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2021 332 270
Genetically Encoded Supramolecular Targeting of Fluorescent Membrane Tension Probes within Live Cells: Precisely Localized Controlled Release by External Chemical StimulationJACS Au
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2021 473 257
Ether lipids, sphingolipids and toxic 1-deoxyceramides as hallmarks for lean and obese type 2 diabetic patientsActa Physiologica
accessLevelRestricted
2021 398 3
Short Photoswitchable Ceramides Enable Optical Control of ApoptosisACS chemical biology
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2021 5 0
Flipper Probes for the CommunityChimia
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2021 462 223
Determination of the lipid composition of the GPI anchorPloS one
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2021 5 18
Patched regulates lipid homeostasis by controlling cellular cholesterol levelsNature communications
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2021 5 8
HaloFlippers: a General Tool for the Fluorescence Imaging of Precisely Localized Membrane Tension Changes in Living CellsACS Central Science
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2020 436 291
Combined Omics Approach Identifies Gambogic Acid and Related Xanthones as Covalent Inhibitors of the Serine Palmitoyltransferase ComplexCell Chemical Biology
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2020 281 0
Vesicular and non-vesicular lipid export from the ER to the secretory pathwayBiochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
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2020 388 0
Conserved Functions of Ether Lipids and Sphingolipids in the Early Secretory PathwayCurrent Biology
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2020 447 286
Luciferase-Induced Photouncaging: BioluminolysisAngewandte Chemie: International Edition
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2019 513 531
A Chemogenetic Approach for the Optical Monitoring of Voltage in NeuronsAngewandte Chemie: International Edition
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2019 299 184
Yeast ceramide synthases, Lag1 and Lac1, have distinct substrate specificityJournal of Cell Science
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2019 360 223
Lysosome-targeted photoactivation reveals local sphingosine metabolism signaturesChemical Science
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2019 512 253
Optical control of sphingosine-1-phosphate formation and functionNature chemical biology
accessLevelRestricted
2019 281 0
Sphingolipids and membrane targets for therapeuticsCurrent Opinion in Chemical Biology
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2019 556 3
On the road to unraveling the molecular functions of ether lipidsFEBS Letters
accessLevelRestricted
2019 305 0
Cytotoxicity of 1-deoxysphingolipid unraveled by genome-wide genetic screens and lipidomics in Saccharomyces cerevisiaeMolecular Biology of the Cell
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2019 282 0
Mitochondrial arginase-2 is a cell‑autonomous regulator of CD8+ T cell function and antitumor efficacyJCI Insight
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2019 389 265
Mitochondria-specific photoactivation to monitor local sphingosine metabolism and functioneLife
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2018 583 353
Lysophospholipids Facilitate COPII Vesicle FormationCurrent Biology
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2018 312 238
Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscleeLife
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2018 588 224
Understanding the diversity of membrane lipid compositionNature Reviews Molecular Cell Biology
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2018 377 0
Mitochondrial disruption in peroxisome deficient cells is hepatocyte selective but is not mediated by common hepatic peroxisomal metabolitesMitochondrion
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2018 302 0
Structure–function insights into direct lipid transfer between membranes by Mmm1–Mdm12 of ERMESJournal of Cell Biology
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2018 401 389
Macrophages release plasma membrane-derived particles rich in accessible cholesterolProceedings of the National Academy of Sciences
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2018 292 0
mTORC2 Promotes Tumorigenesis via Lipid SynthesisCancer Cell
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2017 304 508
Sphingolipid metabolic flow controls phosphoinositide turnover at the trans‐Golgi networkEMBO Journal
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2017 261 0
Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiencyJournal of Clinical Investigation
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2017 320 193
Structure and conserved function of iso-branched sphingoid bases from the nematode Caenorhabditis elegansChemical Science
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2017 265 161
Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitroProceedings of the National Academy of Sciences
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2017 803 0
Detection of genome-edited mutant clones by a simple competition-based PCR methodPLOS ONE
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2017 288 189
Identification and Mode of Action of a Plant Natural Product Targeting Human Fungal PathogensAntimicrobial Agents and Chemotherapy
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2017 581 360
Membrane Phosphoproteomics of Yeast Early Response to Acetic Acid: Role of Hrk1 Kinase and Lipid Biosynthetic Pathways, in Particular SphingolipidsFrontiers in Microbiology
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2017 335 201
The SAGA complex, together with transcription factors and the endocytic protein Rvs167p, coordinates the reprofiling of gene expression in response to changes in sterol composition in Saccharomyces cerevisiaeMolecular Biology of the Cell
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2017 504 0
A method for analysis and design of metabolism using metabolomics data and kinetic models: Application on lipidomics using a novel kinetic model of sphingolipid metabolismMetabolic Engineering
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2016 232 116
Making Sense of the Yeast Sphingolipid PathwayJournal of Molecular Biology
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2016 249 0
Limited ER quality control for GPI-anchored proteinsJournal of Cell Biology
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2016 196 0
Trafficking of glycosylphosphatidylinositol anchored proteins from the endoplasmic reticulum to the cell surfaceJournal of Lipid Research
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2016 247 0
Prolonged starvation drives reversible sequestration of lipid biosynthetic enzymes and organelle reorganization in Saccharomyces cerevisiaeMolecular Biology of the Cell
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2015 202 0
Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviourNature
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2015 236 1
D38-cholesterol as a Raman active probe for imaging intracellular cholesterol storageJournal of Biomedical Optics
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2015 250 146
The SwissLipids knowledgebase for lipid biologyBioinformatics
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2015 266 146
Intracellular sphingosine releases calcium from lysosomeseLife
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2015 244 127
LAPTM4B facilitates late endosomal ceramide export to control cell death pathwaysNature chemical biology
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2015 202 0
Autophagy Competes for a Common Phosphatidylethanolamine Pool with Major Cellular PE-Consuming Pathways in Saccharomyces cerevisiaeGenetics
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2015 199 0
COPII Coat Composition Is Actively Regulated by Luminal Cargo MaturationCurrent Biology
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2015 207 130
HCV 3a core protein increases lipid droplet cholesteryl ester content via a mechanism dependent on sphingolipid biosynthesisPloS one
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2014 602 256
A Fluorogenic Probe for SNAP-Tagged Plasma Membrane Proteins Based on the Solvatochromic Molecule Nile RedACS Chemical Biology
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2014 235 0
Synthetic Multivalent Antifungal Peptides Effective against FungiPLOS ONE
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2014 252 158
Sphingolipid homeostasis in the web of metabolic routesBiochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
accessLevelRestricted
2014 255 1
Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasisMolecular Biology of the Cell
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2014 560 311
Lipidomic Profiling of Saccharomyces cerevisiae and Zygosaccharomyces bailii Reveals Critical Changes in Lipid Composition in Response to Acetic Acid StressPLOS ONE
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2013 271 200
The Peroxisomal Enzyme L-PBE Is Required to Prevent the Dietary Toxicity of Medium-Chain Fatty AcidsCell Reports
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2013 275 109
The Yeast P5 Type ATPase, Spf1, Regulates Manganese Transport into the Endoplasmic ReticulumPLOS ONE
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2013 249 189
TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and AutophagyCell Reports
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2013 229 158
Dynamic Amphiphile Libraries To Screen for the "Fragrant" Delivery of siRNA into HeLa Cells and Human Primary FibroblastsJournal of the American Chemical Society
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2013 700 404
Yeast as a model system for studying lipid homeostasis and functionFEBS Letters
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2012 352 258
Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesisNature cell biology
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2012 1,071 2
Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cellsJournal of lipid research
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2012 716 517
Glycosylphosphatidylinositol anchors regulate glycosphingolipid levelsJournal of Lipid Research
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2012 393 0
Amphiphilic dynamic NDI and PDI probes: imaging microdomains in giant unilamellar vesiclesOrganic & biomolecular chemistry
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2012 816 314
Rsp5 Ubiquitin Ligase Is Required for Protein Trafficking in Saccharomyces cerevisiae COPI MutantsPLOS ONE
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2012 256 134
Loss of ceramide synthase 3 causes lethal skin barrier disruptionHuman Molecular Genetics
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2012 264 132
Chemical Biology Approaches to Membrane Homeostasis and FunctionChimia
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2011 818 83
Mathematical Modeling and Validation of the Ergosterol Pathway in Saccharomyces cerevisiaePLOS ONE
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2011 322 146
Disruption of the ceramide synthase LOH1 causes spontaneous cell death in Arabidopsis thalianaNew Phytologist
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2011 245 0
Conceptually New Entries into CellsChimia
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2011 681 170
NCCR Chemical Biology: Interdisciplinary Research Excellence, Outreach, Education, and New Tools for SwitzerlandChimia
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2011 222 154
A Systems Biology Approach Reveals the Role of a Novel Methyltransferase in Response to Chemical Stress and Lipid HomeostasisPLOS Genetics
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2011 233 80
A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistanceMetabolic Engineering
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2011 242 1
An efficient method for the production of isotopically enriched cholesterol for NMRJournal of lipid research
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2011 716 0
Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPIJournal of Cell Biology
accessLevelRestricted
2011 196 0
Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid MetabolismStructure
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2010 227 164
Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiologyMolecular biology of the cell
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2009 743 584
Methylation of the Sterol Nucleus by STRM-1 Regulates Dauer Larva Formation in Caenorhabditis elegansDevelopmental Cell
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2009 293 0
Protection of C. elegans from anoxia by HYL-2 ceramide synthaseScience
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2009 822 818
The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular OrganizationChimia
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2009 258 173
Concentration of GPI-anchored proteins upon ER exit in yeastTraffic
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2009 651 0
History of Biochemistry at the University of Geneva: From the Boulevard des Philosophes to Quai Ernest-AnsermetChimia
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2009 267 160
Identifying Key Residues of Sphinganine-1-phosphate Lyase for Function in Vivo and in VitroJournal of Biological Chemistry
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2008 189 0
The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatusJournal of Cell Biology
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2008 326 98
Yeast ARV1 Is Required for Efficient Delivery of an Early GPI Intermediate to the First Mannosyltransferase during GPI Assembly and Controls Lipid Flow from the Endoplasmic ReticulumMolecular Biology of the Cell
accessLevelRestricted
2008 207 0
Natamycin Blocks Fungal Growth by Binding Specifically to Ergosterol without Permeabilizing the MembraneThe Journal of biological chemistry
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2008 667 2
Distinct acto/myosin-I structures associate with endocytic profiles at the plasma membraneJournal of Cell Biology
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2008 184 0
Sch9 is a major target of TORC1 in Saccharomyces cerevisiaeMolecular cell
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2007 673 0
Proteasome-Independent Functions of Ubiquitin in Endocytosis and SignalingScience
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2007 587 0
The long and short of fatty acid synthesisCell
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2007 636 1
TEDS Site Phosphorylation of the Yeast Myosins I Is Required for Ligand-induced but Not for Constitutive Endocytosis of the G Protein-coupled Receptor Ste2pJournal of Biological Chemistry
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2006 357 0
Transmembrane topology of ceramide synthase in yeastBiochemical journal
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2006 617 0
Organization and functions of sphingolipid biosynthesis in yeastBiochemical Society Transactions
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2006 216 0
Sphingoid base is required for translation initiation during heat stress in Saccharomyces cerevisiaeMolecular biology of the cell
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2006 525 0
Where sterols are required for endocytosisBiochimica et biophysica acta
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2004 490 0
Why Do Cells Require Heat Shock Proteins to Survive Heat Stress?Cell cycle
accessLevelRestricted
2004 246 0
Sorting GPI-anchored proteinsNature reviews. Molecular cell biology
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2004 71 0
Differential ER exit in yeast and mammalian cellsCurrent Opinion in Cell Biology
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2004 241 0
Lipid pickup and deliveryNature cell biology
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2004 67 0
Lcb4p is a key regulator of ceramide synthesis from exogenous long chain sphingoid base in saccharomyces cerevisiaeThe Journal of biological chemistry
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2003 173 50
Genetic and biochemical interactions between the Arp2/3 complex, Cmd1p, casein kinase II, and Tub4p in yeastFEMS yeast research
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2003 493 1
Drs2p-related P-type ATPases Dnf1p and Dnf2p Are Required for Phospholipid Translocation across the Yeast Plasma Membrane and Serve a Role in EndocytosisMolecular biology of the cell
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2003 486 0
Ordering of Compartments in the Yeast Endocytic PathwayTraffic
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2002 64 68
Biosynthesis and trafficking of sphingolipids in the yeast Saccharomyces cerevisiaeBiochemistry
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2002 527 0
Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cellsThe Journal of biological chemistry
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2002 128 118
Sphingolipids are required for the stable membrane association of glycosylphosphatidylinositol-anchored proteins in yeastThe Journal of biological chemistry
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2002 212 139
Rho1p mutations specific for regulation of β(1→3)glucan synthesis and the order of assembly of the yeast cell wallMolecular microbiology
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2002 53 0
Identification and characterization of Saccharomyces cerevisiae mutants defective in fluid‐phase endocytosisYeast
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2001 58 0
Protein Sorting upon Exit from the Endoplasmic ReticulumCell
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2001 510 1
Rvs161p and Rvs167p, the two yeast amphiphysin homologs, function together in vivoThe Journal of biological chemistry
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2001 141 52
Interdependence of filamentous actin and microtubules for asymmetric cell divisionBiological chemistry
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2000 527 458
Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositolThe Journal of biological chemistry
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1999 108 124
Down regulation of yeast G protein-coupled receptorsSeminars in cell & developmental biology
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1998 69 0
Actin-, myosin-and ubiquitin-dependent endocytosisExperientia
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1996 128 141
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