Comparative effectiveness of TNF inhibitors and tocilizumab with and without conventional synthetic disease-modifying antirheumatic drugs in a pan-European observational cohort of bio-naïve patients with rheumatoid arthritis

Lauper, Kim; Mongin, Denis; Iannone, Florenzo; Kristianslund, Eirik K; Kvien, Tore K; Nordström, Dan C; Pavelka, Karel; Pombo-Suarez, Manuel; Rotar, Ziga; Santos, Maria J; Codreanu, Catalin; Lukina, Galina; Gale, Sara L; John, Markus; Luder, Yves; Courvoisier, Delphine; Gabay, Cem

doi:10.1016/j.semarthrit.2019.06.020

Scientific article

English

Comparative effectiveness of TNF inhibitors and tocilizumab with and without conventional synthetic disease-modifying antirheumatic drugs in a pan-European observational cohort of bio-naïve patients with rheumatoid arthritis

Published inSeminars in Arthritis and Rheumatism

Publication date2019

Abstract

To compare treatment effectiveness in rheumatoid arthritis (RA) patients naïve to biological disease-modifying antirheumatic drugs (bDMARDs) treated with tocilizumab (TCZ) or TNF-inhibitor (TNFi) with (-combo) or without (-mono) conventional synthetic DMARDs (csDMARDs).

Keywords

Biological therapies
DMARDs
Monotherapy
Rheumatoid arthritis
TNF inhibitors
Tocilizumab

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Citation (ISO format)

LAUPER, Kim et al. Comparative effectiveness of TNF inhibitors and tocilizumab with and without conventional synthetic disease-modifying antirheumatic drugs in a pan-European observational cohort of bio-naïve patients with rheumatoid arthritis. In: Seminars in Arthritis and Rheumatism, 2019. doi: 10.1016/j.semarthrit.2019.06.020

Article (Published version)

CC BY-NC-ND

Identifiers

PID : unige:128225
DOI : 10.1016/j.semarthrit.2019.06.020
PMID : 31280937

Journal ISSN0049-0172

323views

252downloads

Creation06/01/2020 08:03:00

First validation06/01/2020 08:03:00

Update03/02/2025 12:54:37

Status update03/02/2025 12:54:37

Last indexation03/02/2025 13:00:09

Archive ouverte UNIGE

Comparative effectiveness of TNF inhibitors and tocilizumab with and without conventional synthetic disease-modifying antirheumatic drugs in a pan-European observational cohort of bio-naïve patients with rheumatoid arthritis

To compare treatment effectiveness in rheumatoid arthritis (RA) patients naïve to biological disease-modifying antirheumatic drugs (bDMARDs) treated with tocilizumab (TCZ) or TNF-inhibitor (TNFi) with (-combo) or without (-mono) conventional synthetic DMARDs (csDMARDs).

Technical informations