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Title

Comparison of analytical performances of the Roche Cobas 6800 CT/NG assay with the Abbott m2000 Real Time CT/NG assay for detecting Chlamydia trachomatis and Neisseria gonorrhoeae

Authors
Mombelli, Michèle
Jaton, Katia
Published in Journal of Medical Microbiology. 2019, vol. 68, no. 2, p. 197-200
Abstract The Roche Cobas 6800 CT/NG assay was compared to the Abbott m2000 Real Time CT/NG assay for detecting Chlamydia trachomatis and Neisseria gonorrhoeae in 714 specimens referred to the bacteriology laboratory at Geneva University Hospitals, between November 2017 and March 2018, and in nine external quality controls for molecular diagnostics (seven from QCMD Glasgow and two from UK NEQAS). For C. trachomatis, the sensitivity of C6800 compared to m2000 was 100 % (95 % confidence interval [CI], 97.5 to 100 %), the specificity was 99.1 % (95 % CI, 98.0 to 99.7 %). For N. gonorrhoeae, the sensitivity of the C6800 compared to m2000 was 100 % (95 % CI, 90.5 to 100 %), whereas the specificity was 99.7 % (95 % CI, 98.9 to 99.9 %). The C6800 CT/NG assay appears to perform with great accuracy the detection of C. trachomatis and N. gonorrhoeae.
Keywords AdolescentAdultAged80 and overAnal Canal/microbiologyChildChlamydia trachomatis/genetics/isolation & purificationFemaleHumansMaleMiddle AgedNeisseria gonorrhoeae/genetics/isolation & purificationOropharynx/microbiologyPredictive Value of TestsProspective StudiesReal-Time Polymerase Chain Reaction/standardsRectum/microbiologyRetrospective StudiesSensitivity and SpecificityUrine/microbiologyVagina/microbiologyYoung Adult
Identifiers
PMID: 30605081
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Research groups Chimie et protéomique clinique (270)
Groupe Laurent Kaiser (virologie clinique) (668)
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CHERKAOUI, Abdessalam et al. Comparison of analytical performances of the Roche Cobas 6800 CT/NG assay with the Abbott m2000 Real Time CT/NG assay for detecting Chlamydia trachomatis and Neisseria gonorrhoeae. In: Journal of Medical Microbiology, 2019, vol. 68, n° 2, p. 197-200. doi: 10.1099/jmm.0.000909 https://archive-ouverte.unige.ch/unige:121605

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Deposited on : 2019-08-15

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