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Anti-apolipoprotein A-1 autoantibodies correlate with disease activity in systemic lupus erythematosus

Published inRheumatology
Publication date2019
Abstract

Apolipoprotein A-1 (ApoA-1) is a protein fraction of the high-density lipoproteins with anti-inflammatory and antioxidant properties that play a major role in reverse cholesterol transport. The presence of anti-ApoA-1 IgG has been reported in SLE to be variably associated with disease activity or cardiovascular events (CVEs). We assessed the clinical performance of anti-ApoA-1 IgG and of antibodies directed against its immunodominant F3L1 peptide (F3L1 IgG) in a well-characterized Swiss SLE cohort study.

Citation (ISO format)
NIGOLIAN, Haig et al. Anti-apolipoprotein A-1 autoantibodies correlate with disease activity in systemic lupus erythematosus. In: Rheumatology, 2019. doi: 10.1093/rheumatology/kez306
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Journal ISSN1462-0324
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Creation14/08/2019 12:54:00
First validation14/08/2019 12:54:00
Update time03/02/2025 12:57:14
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