Scientific Article
previous document  unige:11694  next document
add to browser collection
Title

Heliotropamide, a novel oxopyrrolidine-3-carboxamide from Heliotropium ovalifolium

Authors
Ioset, Jean-Robert
Queiroz, Emerson Ferreira
Sandor, P.
Foggin, C.M.
Published in Journal of Natural Products. 2003, vol. 66, no. 12, p. 1550-1553
Abstract Heliotropamide (1), a new alkaloid with a novel oxopyrrolidine-3-carboxamide central moiety, has been isolated as the major product of the dicholoromethane extract of Heliotropium ovalifolium aerial parts. Its structure was elucidated by spectrometric methods including ESI-HR, EI, D/CI mass spectrometry, H-1, C-13, and 2D NMR experiments, and chemical derivatization. Neither heliotropamide nor its acetylated derivative (1a) showed any antifungal activity against Cladosporium cucumerinum and Candida albicans, antibacterial activity against Bacillus subtilis, radical-scavenging properties in the DPPH test, or inhibitory potential toward acetylcholinesterase.
Keywords New alkaloid,Heliotropium ovalifolium, ESI-HR, EI, D/CI mass spectrometry, H-1, C-13, and 2D NMR,DPPH test
Identifiers
Full text
Article (Published version) (186 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Citation
(ISO format)
GUNTERN, Mathieu et al. Heliotropamide, a novel oxopyrrolidine-3-carboxamide from Heliotropium ovalifolium. In: Journal of Natural Products, 2003, vol. 66, n° 12, p. 1550-1553. https://archive-ouverte.unige.ch/unige:11694

172 hits

0 download

Update

Deposited on : 2010-08-31

Export document
Format :
Citation style :