Heliotropamide, a novel oxopyrrolidine-3-carboxamide from Heliotropium ovalifolium

Article Article scientifique Article Heliotropamide, a novel oxopyrrolidine-3-carboxamide from Heliotropium ovalifolium eng 2003 author Guntern Mathieu 675680 author Ioset Jean-Robert author Queiroz Emerson Ferreira author Sandor P. author Foggin C.M. author Hostettmann Kurt 135647 1550-1553 10.10211np0302495 0163-3864 Heliotropamide (1), a new alkaloid with a novel oxopyrrolidine-3-carboxamide central moiety, has been isolated as the major product of the dicholoromethane extract of Heliotropium ovalifolium aerial parts. Its structure was elucidated by spectrometric methods including ESI-HR, EI, D/CI mass spectrometry, H-1, C-13, and 2D NMR experiments, and chemical derivatization. Neither heliotropamide nor its acetylated derivative (1a) showed any antifungal activity against Cladosporium cucumerinum and Candida albicans, antibacterial activity against Bacillus subtilis, radical-scavenging properties in the DPPH test, or inhibitory potential toward acetylcholinesterase. New alkaloid,Heliotropium ovalifolium, ESI-HR, EI, D/CI mass spectrometry, H-1, C-13, and 2D NMR,DPPH test true Journal of natural products 66 12 20e6e947-383d-42e0-a123-a305c5d7c775 Article (Published version) Restricted Guntern_JNatPro._2003pdf.pdf 190072 application/pdf restrictedAccess

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Heliotropamide, a novel oxopyrrolidine-3-carboxamide from Heliotropium ovalifolium	Journal of natural products			2003	534	0

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Guntern, Mathieu