Urinary steroid profiling in women hints at a diagnostic signature of the polycystic ovary syndrome: A pilot study considering neglected steroid metabolites

Dhayat, Nasser A; Marti, Nesa; Kollmann, Zahraa; Troendle, Amineh; Bally, Lia; Escher, Geneviève; Grössl, Michael; Ackermann, Daniel; Ponte, Belen; Pruijm, Menno; Müller, Michael; Vogt, Bruno; Birkhäuser, Martin H; Bochud, Murielle; Flück, Christa E

doi:10.1371/journal.pone.0203903

Scientific article

English

Urinary steroid profiling in women hints at a diagnostic signature of the polycystic ovary syndrome: A pilot study considering neglected steroid metabolites

ContributorsDhayat, Nasser A; Marti, Nesa; Kollmann, Zahraa; Troendle, Amineh; Bally, Lia; Escher, Geneviève; Grössl, Michael; Ackermann, Daniel; Ponte, Belen; Pruijm, Menno; Müller, Michael; Vogt, Bruno; Birkhäuser, Martin H; Bochud, Murielle; Flück, Christa E

Published inPLOS ONE, vol. 13, no. 10, e0203903

Publication date2018

Abstract

Although the polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women with vast metabolic consequences, its etiology remains unknown and its diagnosis is still made by exclusion. This study aimed at characterizing a large number of urinary steroid hormone metabolites and enzyme activities in women with and without PCOS in order to test their value for diagnosing PCOS.

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Groupe Pierre-Yves Martin (néphrologie) (30)

Citation (ISO format)

DHAYAT, Nasser A et al. Urinary steroid profiling in women hints at a diagnostic signature of the polycystic ovary syndrome: A pilot study considering neglected steroid metabolites. In: PLOS ONE, 2018, vol. 13, n° 10, p. e0203903. doi: 10.1371/journal.pone.0203903

Article (Published version)

CC BY

Identifiers

PID : unige:115361
DOI : 10.1371/journal.pone.0203903
PMID : 30308019

Journal ISSN1932-6203

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Creation16/11/2018 14:06:00

First validation16/11/2018 14:06:00

Update time15/03/2023 16:02:46

Status update15/03/2023 16:02:45

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Urinary steroid profiling in women hints at a diagnostic signature of the polycystic ovary syndrome: A pilot study considering neglected steroid metabolites

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