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Scientific article
English

Cell-free nucleic acids are present in blood products and regulate genes of innate immune response

Published inTransfusion, vol. 58, no. 7, p. 1671-1681
Publication date2018
Abstract

Extracellular nucleic acids circulate in plasma. They are expected to be present in manufactured blood products eligible for transfusion, but little is known about their biological activity on human cells. The aim of this study is to investigate whether cell-free nucleic acids (CFNAs) are present and biologically active in red blood cell units (RBCUs), fresh frozen plasmas, and platelet concentrates.

Citation (ISO format)
WALDVOGEL ABRAMOWSKI, Sophie et al. Cell-free nucleic acids are present in blood products and regulate genes of innate immune response. In: Transfusion, 2018, vol. 58, n° 7, p. 1671–1681. doi: 10.1111/trf.14613
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Article (Published version)
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ISSN of the journal0041-1132
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Creation10/29/2018 2:48:00 PM
First validation10/29/2018 2:48:00 PM
Update time03/15/2023 4:01:30 PM
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