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Ca(2+)-storage organelles |
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Published in | FEBS letters. 1991, vol. 285, no. 2, p. 225-229 | |
Abstract | Intracellular Ca(2+)-storage organelles are found in virtually all eukaryotic cells. They play an important role in the regulation of the cytosolic free Ca2+ concentration and, thereby, in the regulation of cellular activity. Ca(2+)-storage organelles consist, in the simplest model of a Ca2+ pump, of a Ca(2+)-storage protein and a Ca(2+)-release channel. The primary structure of these functionally important proteins of Ca(2+)-storage organelles is similar in different cell types and conserved through evolution. In contrast, their spatial arrangement and, thus, the architecture of Ca(2+)-storage organelles may vary dramatically from one cell type to another. | |
Keywords | Biological Transport, Active — Calcium/ metabolism — Calcium Channels/metabolism — Calcium-Binding Proteins/ metabolism — Calreticulin — Calsequestrin/metabolism — Endoplasmic Reticulum — Models, Biological — Organelles/ metabolism — Sarcoplasmic Reticulum | |
Identifiers | PMID: 1649772 | |
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Citation (ISO format) | KRAUSE, Karl-Heinz. Ca(2+)-storage organelles. In: FEBS letters, 1991, vol. 285, n° 2, p. 225-229. https://archive-ouverte.unige.ch/unige:11389 |