Scientific article

Neutrophil microdomains: linking heterocellular interactions with vascular injury

Published inCurrent Opinion in Hematology, vol. 17, no. 1, p. 25-30
Publication date2010

Neutrophil infiltration is an important feature in inflammatory scenarios. Before these cells infiltrate tissues, however, they contribute to crucial intravascular events in which neutrophil microdomains mediate heterotypic interactions with endothelial cells, red blood cells and/or platelets. In vascular diseases, this can result in exacerbated neutrophil activation, subsequent vascular injury and obstruction of microcirculatory blood flow. This review discusses recent advances in elucidating these neutrophil domains and their associated functions in cell adhesion.

  • Blood Platelets/chemistry/metabolism
  • Blood Vessels/injuries
  • Cell Adhesion
  • Erythrocytes/chemistry
  • Membrane Microdomains/chemistry/metabolism
  • Neutrophil Infiltration
  • Neutrophils/chemistry
Affiliation Not a UNIGE publication
Citation (ISO format)
SCHEIERMANN, Christoph et al. Neutrophil microdomains: linking heterocellular interactions with vascular injury. In: Current Opinion in Hematology, 2010, vol. 17, n° 1, p. 25–30. doi: 10.1097/MOH.0b013e328333d2a3
Main files (1)
Article (Published version)
ISSN of the journal1065-6251

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