en
Scientific article
Case report
English

Imaging mass spectrometry of elements in forensic cases by LA-ICP-MS

Published inInternational Journal of Legal Medicine, vol. 131, no. 2, p. 497-500
Publication date2017
Abstract

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) was performed to map elements in thin formalin-fixed paraffin-embedded tissue sections of two forensic cases with firearm and electrocution injuries, respectively. In both cases, histological examination of the wounded tissue regions revealed the presence of exogenous aggregates that may be interpreted as metallic depositions. The use of imaging LA-ICP-MS allowed us to unambiguously determine the elemental composition of the observed aggregates assisting the pathologist in case assessments. To the best of our knowledge, we demonstrate for the first time the use of imaging LA-ICP-MS as a complementary tool for forensic pathologists and toxicologists in order to map the presence of metals and other elements in thin tissue sections of post-mortem cases.

Keywords
  • Adult
  • Electric Injuries/pathology
  • Humans
  • Lasers, Solid-State
  • Male
  • Mass Spectrometry/methods
  • Middle Aged
  • Skin/chemistry/pathology
  • Trace Elements/analysis
  • Wounds, Gunshot/pathology
Citation (ISO format)
LAUER, Estelle et al. Imaging mass spectrometry of elements in forensic cases by LA-ICP-MS. In: International Journal of Legal Medicine, 2017, vol. 131, n° 2, p. 497–500. doi: 10.1007/s00414-016-1414-4
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Article (Published version)
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Identifiers
ISSN of the journal0937-9827
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