Imaging mass spectrometry of elements in forensic cases by LA-ICP-MS

Article Article scientifique Rapport de cas Imaging mass spectrometry of elements in forensic cases by LA-ICP-MS eng 2017 author Lauer Estelle 686254 author Villa Max 696741 author Jotterand Morgane author Vilarino Raquel 541847 author Bollmann Marc author Michaud Katarzyna author Grabherr Silke 746290 author Augsburger Marc 677425 author Thomas Aurélien 647674 497-500 10.1007/s00414-016-1414-4 27507011 0937-9827 Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) was performed to map elements in thin formalin-fixed paraffin-embedded tissue sections of two forensic cases with firearm and electrocution injuries, respectively. In both cases, histological examination of the wounded tissue regions revealed the presence of exogenous aggregates that may be interpreted as metallic depositions. The use of imaging LA-ICP-MS allowed us to unambiguously determine the elemental composition of the observed aggregates assisting the pathologist in case assessments. To the best of our knowledge, we demonstrate for the first time the use of imaging LA-ICP-MS as a complementary tool for forensic pathologists and toxicologists in order to map the presence of metals and other elements in thin tissue sections of post-mortem cases. Adult Electric Injuries/pathology Humans Lasers, Solid-State Male Mass Spectrometry/methods Middle Aged Skin/chemistry/pathology Trace Elements/analysis Wounds, Gunshot/pathology Dewey 614.1 67 Institut de médecine légale 22A2 false 959 Groupe Silke Grabherr 969 International Journal of Legal Medicine 131 2 8e9668db-b10b-49bb-96d5-c3f83381f672 Article (Published version) Restricted Lauer2017_Article_ImagingMassSpectrometryOfEleme.pdf 2246138 application/pdf restrictedAccess Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires / Institut de médecine légale

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Imaging mass spectrometry of elements in forensic cases by LA-ICP-MS	International Journal of Legal Medicine			2017	412	1

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Villa, Max