Insufficient recruitment and premature discontinuation of clinical trials in Switzerland: qualitative study with trialists and other stakeholders

Briel, Matthias; Elger, Bernice Simone; Von Elm, Erik Bjorn; Satalkar, Priya

doi:10.4414/smw.2017.14556

Scientific article

Open access

English

Insufficient recruitment and premature discontinuation of clinical trials in Switzerland: qualitative study with trialists and other stakeholders

ContributorsBriel, Matthias; Elger, Bernice Simone; Von Elm, Erik Bjorn; Satalkar, Priya

Published inSwiss Medical Weekly, vol. 147, w14556

Publication date2017

Abstract

Premature discontinuation occurs in about 25% of randomised clinical trials in Switzerland; it mainly affects investigator-initiated trials and is mostly due to problems with recruitment of patients. The aim of this study was to qualitatively investigate reasons for trial discontinuation due to poor patient recruitment and suggestions to address those reasons in the Swiss context.

Keywords

Early Termination of Clinical Trials/trends
Humans
Patient Selection
Qualitative Research
Randomized Controlled Trials as Topic
Switzerland

Affiliation

Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires / Institut de médecine légale

Research group

Le Secret médical (676)

Citation (ISO format)

BRIEL, Matthias et al. Insufficient recruitment and premature discontinuation of clinical trials in Switzerland: qualitative study with trialists and other stakeholders. In: Swiss Medical Weekly, 2017, vol. 147, p. w14556. doi: 10.4414/smw.2017.14556

Article (Published version)

Identifiers

PID : unige:111040
DOI : 10.4414/smw.2017.14556
PMID : 29185240

ISSN of the journal1424-7860

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Insufficient recruitment and premature discontinuation of clinical trials in Switzerland: qualitative study with trialists and other stakeholders

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