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Insufficient recruitment and premature discontinuation of clinical trials in Switzerland: qualitative study with trialists and other stakeholders

ContributorsBriel, Matthias; Elger, Bernice Simone; Von Elm, Erik Bjorn; Satalkar, Priya
Published inSwiss Medical Weekly, vol. 147, w14556
Publication date2017
Abstract

Premature discontinuation occurs in about 25% of randomised clinical trials in Switzerland; it mainly affects investigator-initiated trials and is mostly due to problems with recruitment of patients. The aim of this study was to qualitatively investigate reasons for trial discontinuation due to poor patient recruitment and suggestions to address those reasons in the Swiss context.

Keywords
  • Early Termination of Clinical Trials/trends
  • Humans
  • Patient Selection
  • Qualitative Research
  • Randomized Controlled Trials as Topic
  • Switzerland
Affiliation entities
Research groups
Citation (ISO format)
BRIEL, Matthias et al. Insufficient recruitment and premature discontinuation of clinical trials in Switzerland: qualitative study with trialists and other stakeholders. In: Swiss Medical Weekly, 2017, vol. 147, p. w14556. doi: 10.4414/smw.2017.14556
Main files (1)
Article (Published version)
accessLevelPublic
Identifiers
Journal ISSN1424-7860
468views
338downloads

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Creation20/09/2018 13:59:00
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Update15/03/2023 13:50:32
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