Scientific Article
previous document  unige:10566  next document
add to browser collection

Novel basic isoflavones as inhibitors of bone resorption

Delcanale, M.
Amari, G.
Armani, E.
Lipreri, M.
Civelli, M.
Galbiati, E.
Giossi, M.
Caruso, P. L.
show hidden authors show all authors [1 - 11]
Published in Helvetica Chimica Acta. 2001, vol. 84, no. 8, p. 2417-2429
Abstract A number of aminoalkoxy analogues of ipriflavone (=7-(1-methylethoxy)isoflavone) were prepared and examined for their capacity to inhibit bone resorption induced by bovine parathyroid hormone fragment 1 - 34. Good-to-high activities were found for 7-(aminoalkoxy)isoflavone. analogues. Their activity was influenced by a number of structural features, among which the length of the basic side chain, the basicity of the amino group, and the nature and position of substituents on the 3-phenyl ring. 4'-(Aminoalkoxy)ipriflavone derivatives were less active
Full text
Article - document accessible for UNIGE members only Limited access to UNIGE
(ISO format)
DELCANALE, M. et al. Novel basic isoflavones as inhibitors of bone resorption. In: Helvetica Chimica Acta, 2001, vol. 84, n° 8, p. 2417-2429.

389 hits

1 download


Deposited on : 2010-08-06

Export document
Format :
Citation style :