Scientific Article
previous document  unige:10548  next document
add to browser collection
Title

Combined molecular lipophilicity descriptors and their role in understanding intramolecular effects

Authors
Caron, Giulia
Reymond, F.
Girault, H. H.
Testa, Bernard
Published in Pharmaceutical Science & Technology Today. 1999, vol. 2, no. 8, p. 327-335
Abstract Traditional lipophilicity parameters (log P and log D) are well-known physico-chemical descriptors largely used in QSAR studies. Besides their numerical value, log P data contain a variety of information about inter- and intramolecular forces affecting partitioning and its related biological phenomena. The deconvolution of information from log P can be accessed only by adequate interpretative tools, such as new lipophilic-combined descriptors, of which features and some applications are presented in this review.
Identifiers
PMID: 10441277
Full text
Citation
(ISO format)
CARON, Giulia et al. Combined molecular lipophilicity descriptors and their role in understanding intramolecular effects. In: Pharmaceutical Science & Technology Today, 1999, vol. 2, n° 8, p. 327-335. https://archive-ouverte.unige.ch/unige:10548

173 hits

0 download

Update

Deposited on : 2010-08-06

Export document
Format :
Citation style :