Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes

Bugliani, Marco; Wollheim, Claes; Meda, Paolo

doi:10.1007/s00125-017-4500-3

Scientific article

Open access

English

Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes

ContributorsBugliani, Marco; Wollheim, Claes; Meda, Paolo

Published inDiabetologia, vol. 61, no. 3, p. 641-657

Publication date2018

Abstract

Pancreatic islet beta cell failure causes type 2 diabetes in humans. To identify transcriptomic changes in type 2 diabetic islets, the Innovative Medicines Initiative for Diabetes: Improving beta-cell function and identification of diagnostic biomarkers for treatment monitoring in Diabetes (IMIDIA) consortium ( www.imidia.org ) established a comprehensive, unique multicentre biobank of human islets and pancreas tissues from organ donors and metabolically phenotyped pancreatectomised patients (PPP).

Affiliation

Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie

Citation (ISO format)

BUGLIANI, Marco, WOLLHEIM, Claes, MEDA, Paolo. Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes. In: Diabetologia, 2018, vol. 61, n° 3, p. 641–657. doi: 10.1007/s00125-017-4500-3

Article (Published version)

CC BY

Identifiers

PID : unige:104872
DOI : 10.1007/s00125-017-4500-3
PMID : 29185012

ISSN of the journal0012-186X

344views

106downloads

Creation25.05.2018 10:43:00

First validation25.05.2018 10:43:00

Update time15.03.2023 08:16:50

Status update15.03.2023 08:16:49

Last indexation12.02.2024 11:33:00

Archive ouverte UNIGE

Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes

Technical informations