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Medullary-like hepatocellular carcinoma

Cristaudi, Alessandra
Rosso, Raffaele
Varini, Marco
Alerci, Mario
Balzarotti Canger, Ruben Carlo
Published in Journal of Surgical Case Reports. 2018, vol. 2018, no. 2, p. rjy010
Abstract Hepatocellular carcinoma (HCC) is the most frequent primary hepatic cancer. Pathological features can define the biological behavior and prognosis. Medullary-like HCC is a very rare variant that has been described only twice in literature. In the present study, we report the case of a non-cirrhotic 72-year-old man, who presented two HCC lesions on routine screening for hepatitis C virus liver disease. Radiological imaging and biopsy showed two different subtypes: one classic HCC, which was treated with chemoembolization, and a second PET/CT-positive carcinoma with a PET/CT-positive metastatic coeliac lymph node, which was resected laparoscopically with a left lateral sectionectomy and extended lymphadenectomy. Histopathology revealed a medullary-like HCC; lymph node analysis confirmed the metastatic nature of the PET/CT-positive coeliac node and showed an incidental B-cell lymphoma in the hepatic pedicle lymph nodes. To the best of our knowledge this is the third case of medullary-like HCC described in the literature, and the first associated to a concomitant typical HCC.
PMID: 29435219
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Article (Published version) (2.2 MB) - public document Free access
Research groups Chirurgie viscérale (104)
Transplantation et hépatologie (905)
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CRISTAUDI, Alessandra et al. Medullary-like hepatocellular carcinoma. In: Journal of Surgical Case Reports, 2018, vol. 2018, n° 2, p. rjy010. https://archive-ouverte.unige.ch/unige:103522

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Deposited on : 2018-04-13

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