TORC2 Structure and Function
ContributorsGaubitz, Christl; Prouteau, Manoel; Kusmider, Beata; Loewith, Robbie Joséph
Published inTrends in Biochemical Sciences, vol. 41, no. 6, p. 532-545
Publication date2016
Abstract
Keywords
- Animals
- Antibiotics
- Antineoplastic/pharmacology
- Binding Sites
- Gene Expression Regulation
- Humans
- Mechanistic Target of Rapamycin Complex 1
- Mechanistic Target of Rapamycin Complex 2
- Mice
- Mice
- Knockout
- Models
- Molecular
- Multiprotein Complexes/antagonists & inhibitors/chemistry/genetics/metabolism
- Protein Binding
- Protein Conformation
- Alpha-Helical
- Protein Interaction Domains and Motifs
- Protein Subunits/chemistry/genetics/metabolism
- Signal Transduction
- Sirolimus/pharmacology
- Structure-Activity Relationship
- TOR Serine-Threonine Kinases/antagonists & inhibitors/chemistry/genetics/metabolism
Research group
Citation (ISO format)
GAUBITZ, Christl et al. TORC2 Structure and Function. In: Trends in Biochemical Sciences, 2016, vol. 41, n° 6, p. 532–545. doi: 10.1016/j.tibs.2016.04.001
Main files (1)
Article (Published version)
Identifiers
- PID : unige:103222
- DOI : 10.1016/j.tibs.2016.04.001
- PMID : 27161823
ISSN of the journal0968-0004