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Scientific article
English

Tolerance and safety of nifurtimox in patients with chronic chagas disease

ContributorsJackson, Yves-Laurent Julienorcid; Alirol, Emilie; Getaz, Laurent; Wolff, Hans; Combescure, Christopheorcid; Chappuis, François
Published inClinical Infectious Diseases, vol. 51, no. 10, p. e69-75
Publication date2010
Abstract

Nifurtimox has been used to treat Chagas disease for 40 years, but tolerance and safety data in adults are scarce. We aimed to evaluate nifurtimox tolerance and safety in a cohort of Trypanosoma cruzi-infected adult patients in a country of nonendemicity.

Keywords
  • Adolescent
  • Adult
  • Aged
  • Chagas Disease/drug therapy
  • Chronic Disease
  • Female
  • Humans
  • Kaplan-Meier Estimate
  • Latin America/ethnology
  • Longitudinal Studies
  • Male
  • Medication Adherence
  • Middle Aged
  • Nifurtimox/adverse effects/therapeutic use
  • Switzerland
  • Trypanocidal Agents/adverse effects/therapeutic use
Affiliation entities
Research groups
Citation (ISO format)
JACKSON, Yves-Laurent Julien et al. Tolerance and safety of nifurtimox in patients with chronic chagas disease. In: Clinical Infectious Diseases, 2010, vol. 51, n° 10, p. e69–75. doi: 10.1086/656917
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Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN1058-4838
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