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Scientific article
English

Tolerance and safety of nifurtimox in patients with chronic chagas disease

Contributors

Jackson, Yves-Laurent Julien; Alirol, Emilie; Getaz, Laurent; Wolff, Hans; Combescure, Christophe; Chappuis, François

Published in

Clinical Infectious Diseases, vol. 51, no. 10, p. e69-75

Publication date

2010

Abstract

Nifurtimox has been used to treat Chagas disease for 40 years, but tolerance and safety data in adults are scarce. We aimed to evaluate nifurtimox tolerance and safety in a cohort of Trypanosoma cruzi-infected adult patients in a country of nonendemicity.

Keywords

  • Adolescent
  • Adult
  • Aged
  • Chagas Disease/drug therapy
  • Chronic Disease
  • Female
  • Humans
  • Kaplan-Meier Estimate
  • Latin America/ethnology
  • Longitudinal Studies
  • Male
  • Medication Adherence
  • Middle Aged
  • Nifurtimox/adverse effects/therapeutic use
  • Switzerland
  • Trypanocidal Agents/adverse effects/therapeutic use

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

JACKSON, Yves-Laurent Julien et al. Tolerance and safety of nifurtimox in patients with chronic chagas disease. In: Clinical Infectious Diseases, 2010, vol. 51, n° 10, p. e69–75. doi: 10.1086/656917

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

1058-4838
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Technical informations

Creation

20/02/2018 15:15:00

First validation

20/02/2018 15:15:00

Update

15/03/2023 07:53:30

Status update

15/03/2023 07:53:29

Last indexation

31/10/2024 09:40:10
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