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Title

Immune Checkpoint Inhibitor-Associated Myocarditis: A New Challenge for Cardiologists
Authors
Frigeri, Mauro
Meyer, Philippe
Banfi, Carlo
Giraud, Raphaël
Hachulla-Lemaire, Anne-Lise
Spoerl, David
Friedlaender, Alex
Pugliesi - Rinaldi, Angela
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Published in Canadian Journal of Cardiology. 2018, vol. 34, no. 1, p. 92.e1-92.e3
Abstract The ever-increasing use of immune checkpoint inhibitors in cancer is leading to a high incidence of autoimmune side effects. This report discusses an autoimmune fulminant myocarditis in an elderly patient with metastatic pulmonary adenocarcinoma in whom the most advanced invasive heart failure therapies were used successfully. She was treated with nivolumab. This case illustrates a severe cardiovascular complication of immunotherapy and highlights to cardiologists the importance of aggressive treatments in patients with metastatic cancers whose prognosis has improved dramatically.
Identifiers
PMID: 29275889
Full text
Article (Published version) (569 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Faculté de médecine / Section de médecine clinique / Département de médecine interne des spécialités
Faculté de médecine / Section de médecine clinique / Département de chirurgie
Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie et soins intensifs
Research groups Groupe de recherche en hémodynamique (913)
Immunothérapie des cancers (42)
Citation
(ISO format) 		FRIGERI, Mauro et al. Immune Checkpoint Inhibitor-Associated Myocarditis: A New Challenge for Cardiologists. In: Canadian Journal of Cardiology, 2018, vol. 34, n° 1, p. 92.e1-92.e3. https://archive-ouverte.unige.ch/unige:101415

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Deposited on : 2018-01-16

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