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Severe leptospirosis with multiple organ failure successfully treated by plasma exchange and high-volume hemofiltration

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Published in Case Reports in Nephrology and Dialysis. 2011, vol. 2011, p. 817414
Abstract Background. Leptospirosis is a spirochetal zoonosis with complex clinical features including renal and liver failure. Case report. We report the case of a Swiss fisherman presenting with leptospirosis. After initial improvement, refractory septic shock and severe liver and kidney failure developed. The expected mortality was estimated at 90% with clinical scores. The patient underwent plasma exchanges and high-volume hemofiltration (HVHF) with complete recovery of hepatic and kidney functions. Discussion. Plasma exchanges and HVHF may confer survival benefit on patients with severe leptospirosis, refractory septic shock, and multiple-organ failure.
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PMID: 24527237
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Article (Published version) (472 Kb) - public document Free access
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Research group Groupe Pierre-Yves Martin (néphrologie) (30)
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BOURQUIN, Vincent et al. Severe leptospirosis with multiple organ failure successfully treated by plasma exchange and high-volume hemofiltration. In: Case Reports in Nephrology and Dialysis, 2011, vol. 2011, p. 817414. https://archive-ouverte.unige.ch/unige:100663

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Deposited on : 2017-12-20

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