1 - 133 of 133
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Engineered CD4 TCR T cells with conserved high-affinity TCRs targeting NY-ESO-1 for advanced cellular therapies in cancerScience advances
2025 92 212
Acceptability of an Electronic Patient-Reported Outcomes-Based Model of Care to Monitor Symptoms Related to Cancer Treatment with Immune Checkpoint Inhibitors : Results from the IePRO Randomized Controlled TrialSeminars in oncology nursing
2025 6 37
Convergent inducers and effectors of T cell paralysis in the tumour microenvironmentNature reviews. Cancer
2025 61 0
Overall survival of recurrent/metastatic head & neck squamous cell carcinoma patients progressing after ≥ 1 line of systemic therapy, treated with MVX-ONCO-1, a novel, first in class cell encapsulation-based immunotherapy : results of SAKK 11/16, a phase IIa trialExperimental hematology & oncology
2025 60 58
The current landscape of spatial biomarkers for prediction of response to immune checkpoint inhibitionnpj precision oncology
2024 82 33
Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacyCell
2024 994 349
Response to tumor-infiltrating lymphocyte adoptive therapy is associated with preexisting CD8+ T-myeloid cell networks in melanomaScience immunology
2024 291 0
SwissDock 2024: major enhancements for small-molecule docking with Attracting Cavities and AutoDock VinaNucleic acids research
2024 9 447
LBA46 SAKK 11/16, a phase IIa trial evaluating overall survival (OS) for recurrent/metastatic Head & neck squamous cell carcinoma (RMHNSCC) patients (pts) progressing after ≥ 1 line of systemic therapy, treated with MVX-ONCO-1, a novel, first in class cell encapsulation-based immunotherapyESMO Congress 2023
2023 126 148
Single Seminal Vesicle Metastasis From Dorsal Melanoma Detected by 18 F-FDG PET/CT and Confirmed by BiopsyClinical nuclear medicine
2023 3 0
Testing a model of care for patients on immune checkpoint inhibitors based on electronic patient-reported outcomes : protocol for a randomized phase II controlled trialJMIR research protocols
2023 126 222
Neoadjuvant immunotherapy : a promising new standard of careInternational journal of molecular sciences
2023 109 502
Novel targets for immune-checkpoint inhibition in cancerCancer treatment reviews
2023 102 98
Response and Resistance to Trametinib in MAP2K1-Mutant Triple-Negative MelanomaInternational journal of molecular sciences
2023 12 24
Dendritic cells direct circadian anti-tumour immune responsesNature
2023 799 221
Deep and lasting response and acquired resistance to BRAFV600E targeting in a low-grade ovarian cancer patientCancer biology & therapy
2023 100 91
Prognosis of Patients With Primary Melanoma Stage I and II According to American Joint Committee on Cancer Version 8 Validated in Two Independent Cohorts : Implications for Adjuvant TreatmentJournal of clinical oncology
2022 6 33
Towards a national strategy for digital pathology in SwitzerlandVirchows Archiv
2022 245 176
Chemotherapy after immune checkpoint inhibitor failure in metastatic melanoma : a retrospective multicentre analysisEuropean journal of cancer
2022 4 0
Immune checkpoint inhibitor therapy and outcomes from SARS-CoV-2 infection in patients with cancer : a joint analysis of OnCovid and ESMO-CoCARE registriesJournal for immunotherapy of cancer
2022 9 14
Perspectives in Melanoma : meeting report from the Melanoma Bridge (December 2nd - 4th, 2021, Italy)Journal of translational medicine
2022 9 37
Renin–angiotensin–aldosterone system inhibitors and survival in patients with hypertension treated with immune checkpoint inhibitorsEuropean journal of cancer
2022 13 103
Defining unique clinical hallmarks for immune checkpoint inhibitor-based therapiesJournal for immunotherapy of cancer
2022 3 9
Efficacy and safety of anti-PD1 monotherapy or in combination with ipilimumab after BRAF/MEK inhibitors in patients with BRAF mutant metastatic melanomaJournal for immunotherapy of cancer
2022 6 8
Proton Pump Inhibitor Use and Efficacy of Nivolumab and Ipilimumab in Advanced MelanomaCancers
2022 3 50
An International Comparison of Presentation, Outcomes and CORONET Predictive Score Performance in Patients with Cancer Presenting with COVID-19 across Different Pandemic WavesCancers
2022 3 7
COVID-19 in patients with cancer: first report of the ESMO international, registry-based, cohort study (ESMO-CoCARE)ESMO open
2022 3 6
Heterogeneity in Survival with Immune Checkpoint Inhibitors and Its Implications for Survival Extrapolations : A Case Study in Advanced MelanomaMDM policy & practice
2022 6 34
Immune checkpoint inhibitor therapy and outcomes from SARS-CoV-2 infection in patients with cancer : A joint analysis of OnCovid and ESMO-CoCARE registriesESMO Immuno-Oncology Congress 2022
2022 9 8
The SwissSimilarity 2021 Web Tool : Novel Chemical Libraries and Additional Methods for an Enhanced Ligand-Based Virtual Screening ExperienceInternational journal of molecular sciences
2022 4 99
Establishment of CORONET, COVID-19 Risk in Oncology Evaluation Tool, to Identify Patients With Cancer at Low Versus High Risk of Severe Complications of COVID-19 Disease On Presentation to HospitalJCO clinical cancer informatics
2022 4 14
Structure-based prediction of BRAF mutation classes using machine-learning approachesScientific reports
2022 10 9
Identification of New Vulnerabilities in Conjunctival Melanoma Using Image-Based High Content Drug ScreeningCancers
2022 3 38
SwissBioisostere 2021 : updated structural, bioactivity and physicochemical data delivered by a reshaped web interfaceNucleic acids research
2022 4 79
Systematic comparison with autoimmune liver disease identifies specific histological features of immune checkpoint inhibitor-related adverse eventsJournal for immunotherapy of cancer
2022 5 24
Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitorsJournal of enzyme inhibition and medicinal chemistry
2022 5 177
Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanomaJournal for immunotherapy of cancer
2022 4 56
Sustainable responses in metastatic melanoma patients with and without brain metastases after elective discontinuation of anti-PD1-based immunotherapy due to complete responseEuropean journal of cancer
2021 3 26
68Ga-DOTATOC PET/CT to detect immune checkpoint inhibitor-related myocarditisJournal for immunotherapy of cancer
2021 5 8
Real-life use of talimogene laherparepvec (T-VEC) in melanoma patients in centers in Austria, Switzerland and GermanyJournal for immunotherapy of cancer
2021 3 71
Re-induction ipilimumab following acquired resistance to combination ipilimumab and anti-PD-1 therapyEuropean journal of cancer
2021 3 0
Ovarian cancer with high-level focal ERBB2 amplification responds to trastuzumab and pertuzumabGynecologic Oncology Reports
2021 266 134
Ipilimumab versus ipilimumab plus anti-PD-1 for metastatic melanoma - Authors' replyLancet oncology
2021 7 0
Patient-reported outcomes for monitoring symptomatic toxicities in cancer patients treated with immune-checkpoint inhibitors : A Delphi studyEuropean journal of cancer
2021 4 85
Real-life data for first-line combination immune-checkpoint inhibition and targeted therapy in patients with melanoma brain metastasesEuropean journal of cancer
2021 4 44
Pathophysiology, diagnosis and management of cardiac toxicity induced by immune checkpoint inhibitors and BRAF and MEK inhibitorsCancer treatment reviews
2021 4 33
Ipilimumab alone or ipilimumab plus anti-PD-1 therapy in patients with metastatic melanoma resistant to anti-PD-(L)1 monotherapy : a multicentre, retrospective, cohort studyLancet oncology
2021 17 0
Acute cardiac manifestations under immune checkpoint inhibitors — beware of the obvious : a case reportEuropean heart journal. Case reports
2021 11 8
Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell ImmunityCancer discovery
2021 7 8
Swiss-PO : a new tool to analyze the impact of mutations on protein three-dimensional structures for precision oncologynpj precision oncology
2021 5 1
Cystathionine-gamma-lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomyCancer science
2021 9 31
Delayed immune-related adverse events with anti-PD-1-based immunotherapy in melanomaAnnals of oncology
2021 4 54
Structure and Plasticity of Indoleamine 2,3-Dioxygenase 1 (IDO1)Journal of medicinal chemistry
2021 3 64
Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) InhibitorsJournal of medicinal chemistry
2021 5 162
First-Line Selective Internal Radiation Therapy in Patients with Uveal Melanoma Metastatic to the LiverThe Journal of nuclear medicine
2020 5 43
Evolving impact of long-term survival results on metastatic melanoma treatmentJournal for immunotherapy of cancer
2020 4 28
The Great Debate at "Melanoma Bridge", Naples, December 7th, 2019Journal of translational medicine
2020 10 8
Comparison of the clinical utility of two different size next generation sequencing (NGS) gene panels for solid tumoursMolecular Analysis for Precision Oncology (MAP) Virtual Congress 2020
2020 4 22
Encorafenib plus Binimetinib in Patients with locally advanced, inoperable, or metastatic BRAFV600 mutated Melanoma : First Data from the multicenter, multinational, prospective, non-interventional Longitudinal Study BERINGMELANOM30. Deutschen Hautkrebskongresses (ADO-Jahrestagung)
2020 5 7
Trametinib Induces the Stabilization of a Dual GNAQ p.Gly48Leu- and FGFR4 p.Cys172Gly-Mutated Uveal Melanoma. The Role of Molecular Modelling in Personalized OncologyInternational journal of molecular sciences
2020 5 10
Intratumoural immunotherapies for unresectable and metastatic melanoma: current status and future perspectivesBritish journal of cancer
2020 12 7
Integrating radiomics into holomics for personalised oncology : from algorithms to bedsideEuropean radiology experimental
2020 3 32
Supporting Clinical Decision-Making during the SARS-CoV-2 Pandemic through a Global Research Commitment : The TERAVOLT ExperienceCancer cell
2020 4 13
Managing cancer patients during the COVID-19 pandemic : an ESMO multidisciplinary expert consensusAnnals of oncology
2020 5 28
ESMO consensus conference recommendations on the management of locoregional melanoma: under the auspices of the ESMO Guidelines CommitteeAnnals of oncology
2020 4 5
Guillain-Barré syndrome after adoptive cell therapy with tumor-infiltrating lymphocytesJournal for immunotherapy of cancer
2020 9 23
Cytokine-directed therapy with tocilizumab for immune checkpoint inhibitor-related hemophagocytic lymphohistiocytosisAnnals of oncology
2020 3 28
Herpes simplex encephalitis in adult patients with MASP-2 deficiencyPLOS pathogens
2019 8 8
Deep Response to Anti-PD-1 Therapy of Metastatic Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumor With CD274/PD-L1 AmplificationJCO precision oncology
2019 3 0
MedCo : Enabling Secure and Privacy-Preserving Exploration of Distributed Clinical and Genomic DataIEEE/ACM transactions on computational biology and bioinformatics
2019 3 0
Adverse effects of immune-checkpoint inhibitors : epidemiology, management and surveillanceNature reviews. Clinical oncology
2019 5 0
Perspectives in melanoma: meeting report from the Melanoma Bridge (November 29th-1 December 1st, 2018, Naples, Italy)Journal of translational medicine
2019 10 6
Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancerScience translational medicine
2018 3 0
Sensitive and frequent identification of high avidity neo-epitope specific CD8+ T cells in immunotherapy-naive ovarian cancerNature communications
2018 9 47
ECCO essential requirements for quality cancer care : MelanomaCritical reviews in oncology/hematology
2018 4 19
Practice-Changing Developments in Stage III Melanoma : Surgery, Adjuvant Targeted Therapy, and ImmunotherapyAmerican Society of Clinical Oncology educational book
2018 3 26
Benefit of the nivolumab and ipilimumab combination in pretreated advanced melanomaEuropean journal of cancer
2018 3 0
Pan-SRC kinase inhibition blocks B-cell receptor oncogenic signaling in non-Hodgkin lymphomaBlood
2018 4 36
Response to MEK inhibition with trametinib and tyrosine kinase inhibition with imatinib in multifocal histiocytic sarcomaHaematologica
2018 10 5
ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Immune checkpoint inhibitors, cell adhesion inhibitors, sphingosine-1-phosphate receptor modulators and proteasome inhibitors)Clinical microbiology and infection
2018 8 56
Autoimmune Colitis in Patients Undergoing Therapy with Immune Checkpoint Inhibitors : a Case SeriesAnnual Meeting Swiss Society of Gastroenterology (SGG-SSG), Swiss Society of Visceral Surgery (SGVC-SSCV), Swiss Association for the Study of the Liver (SASL,) Swiss Society of Endoscopy Nurses and Associates (SVEP-ASPE)
2018 3 25
T cell receptor alpha variable 12-2 bias in the immunodominant response to Yellow fever virusEuropean Journal of Immunology
2018 6 32
A severe case of neuro-Sjögren's syndrome induced by pembrolizumabJournal for immunotherapy of cancer
2018 8 28
CD73 expression and clinical significance in human metastatic melanomaOncotarget
2018 7 8
A randomized multicenter phase 3 trial of adjuvant fotemustine versus surveillance in high risk uveal melanoma (UM) patients (FOTEADJ)32nd ASCO Annual Meeting
2017 8 13
Combining talimogene laherparepvec with immunotherapies in melanoma and other solid tumorsCancer immunology and immunotherapy
2017 3 24
Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanomaScience translational medicine
2017 6 0
SwissADME : a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small moleculesScientific reports
2017 8 241
Systematic review of the use of granulocyte–macrophage colony-stimulating factor in patients with advanced melanomaCancer immunology and immunotherapy
2016 3 37
Primary analysis of MASTERKEY-265 phase 1b study of talimogene laherparepvec (T-VEC) and pembrolizumab (pembro) for unresectable stage IIIB-IV melanomaMelanoma and immunotherapy bridge 2015
2016 4 3
Safety and anti-tumor activity of Pasireotide in patients with BRAF- and NRAS-wild type, unresectable and or metastatic melanoma : a phase I, open-label, single-arm study16th World Congress on Cancers of the Skin
2016 5 4
ESMO/ASCO recommendations for a Global Curriculum (GC) in medical oncology-edition 2016Annals of oncology
2016 3 41
Attracting cavities for docking. Replacing the rough energy landscape of the protein by a smooth attracting landscapeJournal of computational chemistry
2016 4 79
1,2,3-Triazoles as inhibitors of indoleamine 2,3-dioxygenase 2 (IDO2)Bioorganic & medicinal chemistry letters
2016 7 0
Genomic analysis reveals novel drivers and progression pathways in skin basal cell carcinomaHuman genome meeting 2016
2016 7 12
Gaining momentum : New options and opportunities for the treatment of advanced melanomaCancer treatment reviews
2015 3 0
PrefaceImmuno-Oncology
2015 4 6
Vaccination with long NY-ESO-1 79-108 peptide and CpG-B leads to robust activation of CD4 and CD8 T cell responses in stage III/IV melanoma patients, and a new HLA-DR7 epitope30th Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2015)
2015 3 14
Safety data from the phase 1b part of the MASTERKEY-265 study combining talimogene laherparepvec (T-VEC) and pembrolizumab for unresectable stage IIIB-IV melanomaEuropean Cancer Congress 2015
2015 9 0
Immuno-Oncology
2015 4 18
Real life experience with check point and kinase inhibitors in Swiss advanced melanoma patients2015 ASCO Annual Meeting
2015 3 7
Triple wild type melanoma profiling in the Caris Molecular IntelligenceTM registryEuropean Cancer Congress (ECC 2015)
2015 4 0
Triple wild type melanoma profiling in the Caris Molecular Intelligence registry51st Annual meeting of the American Society of Clinical Oncology (ASCO)
2015 7 15
A Phase I/III, multicenter, open-label trial of talimogene laherparepvec (T-VEC) in combination with pembrolizumab for the treatment of unresected, stage IIIb-IV melanoma (MASTERKEY-265)30th Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2015)
2015 4 24
Vemurafenib in patients with BRAFV600 mutation-positive melanoma with symptomatic brain metastases : final results of an open-label pilot studyEuropean journal of cancer
2014 5 0
MART-1 peptide vaccination plus IMP321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion : results of a Phase I trialJournal of translational medicine
2014 3 29
Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitorsEuropean journal of medicinal chemistry
2014 3 0
FcgRIIIA (CD16)-expressing monocytes mediate the depletion of tumor-infiltrating Tregs via Ipilimumab-dependent ADCC in melanoma patientsSociety for Immunotherapy of Cancer : 29th Annual Meeting
2014 3 31
Frequencies of circulating MDSC correlate with clinical outcome of melanoma patients treated with ipilimumabCancer immunology and immunotherapy
2014 4 29
The Peroxisomal Enzyme L-PBE Is Required to Prevent the Dietary Toxicity of Medium-Chain Fatty AcidsCell Reports
2013 278 130
Prediction of cross-recognition of peptide-HLA A2 by Melan-A-specific cytotoxic T lymphocytes using three-dimensional quantitative structure-activity relationshipsPloS one
2013 4 29
Shaping the interaction landscape of bioactive moleculesBioinformatics
2013 9 32
A dramatic lung cancer course in a patient with a rare EGFR germline mutation exon 21 V843I : Is EGFR TKI resistance predictable ?Lung cancer
2013 4 0
Persistence of EBV antigen-specific CD8 T cell clonotypes during homeostatic immune reconstitution in cancer patientsPloS one
2013 6 38
Lung adenocarcinoma with BRAF G469L mutation refractory to vemurafenibLung cancer
2013 3 0
Nano‐particle vaccination combined with TLR ‐7 and ‐9 ligands triggers memory and effector CD 8 + T ‐cell responses in melanoma patientsEuropean Journal of Immunology
2012 5 14
Expanding molecular modeling and design tools to non‐natural sidechainsJournal of computational chemistry
2012 3 0
Vaccination-induced functional competence of circulating human tumor-specific CD8 T-cellsInternational journal of cancer
2012 7 0
Predictive value of the MGMT promoter methylation status in metastatic melanoma patients receiving first-line temozolomide plus bevacizumab in the trial SAKK 50/07Oncology Reports
2012 3 27
Defining and searching for structural motifs using DeepView/Swiss-PdbViewerBMC bioinformatics
2012 6 7
Identification of human IKK-2 inhibitors of natural origin (Part II) : In Silico prediction of IKK-2 inhibitors in natural extracts with known anti-inflammatory activityEuropean journal of medicinal chemistry
2011 4 0
Unique spectrum of activity of prosimian TRIM5alpha against exogenous and endogenous retrovirusesJournal of virology
2011 7 31
Structure-function analyses point to a polynucleotide-accommodating groove essential for APOBEC3A restriction activitiesJournal of virology
2011 8 8
Identification of human IKK-2 inhibitors of natural origin (part I) : modeling of the IKK-2 kinase domain, virtual screening and activity assaysPloS one
2011 4 10
Rational design of indoleamine 2,3-dioxygenase inhibitorsJournal of medicinal chemistry
2010 3 0
Evidence for a TCR affinity threshold delimiting maximal CD8 T cell functionThe Journal of immunology
2010 4 0
Frequent MAGE mutations in human melanomaPloS one
2010 6 29
Use of the FACTS solvation model for protein-ligand docking calculations. Application to EADockJMR. Journal of molecular recognition
2010 4 0
Foreword Preface to the JMR Special Issue on ‘Dynamic Aspects of Molecular Recognition’JMR. Journal of molecular recognition
2010 4 12
MM-GBSA binding free energy decomposition and T cell receptor engineeringJMR. Journal of molecular recognition
2010 4 0
Fourier transform convolution integrals applied to generalized Born molecular volumeJournal of computational chemistry
2010 4 0
A novel population of human melanoma-specific CD8 T cells recognizes Melan-AMART-1 immunodominant nonapeptide but not the corresponding decapeptideThe Journal of immunology
2007 5 0
T cell recognition of hapten. Anatomy of T cell receptor binding of a H-2kd-associated photoreactive peptide derivativeThe Journal of biological chemistry
1999 8 84
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