Two weeks versus four weeks of antibiotic therapy after surgical drainage for native joint bacterial arthritis: a prospective, randomised, non-inferiority trial

Article Article scientifique Article Two weeks versus four weeks of antibiotic therapy after surgical drainage for native joint bacterial arthritis: a prospective, randomised, non-inferiority trial eng 2019 author Gjika Ergys 822830 author Beaulieu Jean-Yves 0000-0002-5537-7505 679969 author Vakalopoulos Konstantinos 934596 author Gauthier Morgan 670219 author Bouvet Cindy 592622 author Gonzalez Amanda 528942 author Morello Vanessa 957007 author Steiger Christina 822484 author Hirsiger Stefanie 867983 author Lipsky Benjamin Alan 793658 author Uckay Ilker 134868 10.1136/annrheumdis-2019-215116 30992295 0003-4967 OBJECTIVE The optimal duration of postsurgical antibiotic therapy for adult native joint bacterial arthritis remains unknown. METHODS We conducted a prospective, unblinded, randomised, non-inferiority study comparing either 2 or 4 weeks of antibiotic therapy after surgical drainage of native joint bacterial arthritis in adults. Excluded were implant-related infections, episodes without surgical lavage and episodes with a follow-up of less than 2 months. Adverse events of antibiotics Antibiotic duration Native joint septic arthritis Randomized clinical trial Sequelae Dewey 617 57 Département de chirurgie 222 false 546 Recherche clinique en chirurgie pédiatrique 886 955 Mécanismes physiopathologiques de l'arthrose 960 Annals of the Rheumatic Diseases 17869461-ba84-4f36-8f31-33bbbd21c726 Article (Published version) Public annrheumdis-2019-215116.full.pdf 624876 application/pdf CC BY-NC 4dcf200b-32b3-4d31-bf49-4690b11c6676 Appendix Restricted annrheumdis-2019-215116-inline-supplementary-material-1.pdf 458712 application/pdf openAccess Faculté de médecine / Section de médecine clinique / Département de chirurgie

Title	Published in	Year	Views	Downloads

Two weeks versus four weeks of antibiotic therapy after surgical drainage for native joint bacterial arthritis: a prospective, randomised, non-inferiority trial	Annals of the Rheumatic Diseases	2019	596	238
Revision rate after screw or plate arthrodesis of the glenohumeral joint	Orthopaedics & Traumatology, Surgery & Research	2017	498	0

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Hirsiger, Stefanie