Life-course socioeconomic status and DNA methylation of genes regulating inflammation

Article Article scientifique Article Life-course socioeconomic status and DNA methylation of genes regulating inflammation eng 2015 author Stringhini Silvia 830749 author Polidoro Silvia author Sacerdote Carlotta author Kelly Rachel S author van Veldhoven Karin author Agnoli Claudia author Grioni Sara author Tumino Rosario author Giurdanella Maria Concetta author Panico Salvatore author Mattiello Amalia author Palli Domenico author Masala Giovanna author Gallo Valentina Santina 809674 author Castagné Raphaële author Paccaud Fred author Campanella Gianluca author Chadeau-Hyam Marc author Vineis Paolo 1320-1330 10.1093/ije/dyv060 25889032 0300-5771 In humans, low socioeconomic status (SES) across the life course is associated with greater diurnal cortisol production, increased inflammatory activity and higher circulating antibodies for several pathogens, all suggesting a dampened immune response. Recent evidence suggests that DNA methylation of pro-inflammatory genes may be implicated in the biological embedding of the social environment. DNA Methylation Female Genome-Wide Association Study Healthy Volunteers Humans Inflammation/genetics Italy Male Middle Aged Multivariate Analysis NFATC Transcription Factors/genetics Prospective Studies Social Class Social Environment Swiss National Science Foundation Socioeconomic status and cardio-metabolic disease: an epidemiological perspective on the biology of social adversity 147998 CH Careers true International Journal of Epidemiology 44 4 000e99d6-5d36-40ba-b6c7-9f4a62fba3bd Article (Published version) Public dyv060.pdf 520567 application/pdf OA OTHER openAccess

Title	Published in	Access level	OA Policy	Year	Views	Downloads

Life-course socioeconomic status and DNA methylation of genes regulating inflammation	International Journal of Epidemiology			2015	172	281

Archive ouverte UNIGE

Gallo, Valentina Santina