Influence of population structure on the rate of molecular evolution

Diplôme Master Influence of population structure on the rate of molecular evolution eng 2018 author Bizet Elisabeth 778723 director Montoya Burgos Juan Ignacio 47049 Almost all species display small to high amount of population structure. Nevertheless, according to theory, the rate of neutral evolution is equal to the mutation rate and is independent from population size or structure. The aim of this master was to check the influence of population structure on the rate of neutral evolution. This was done through the study of species found in literature and with forward population genetic simulations. Non-neutral evolution and subpopulations spatial arrangements were also studied. Most tested candidate species had significant faster rates of molecular evolution than their less structured sister species. Moreover in the simulations, difference in evolutionary rates between structured and unstructured populations were found for both neutral and non-neutral evolution. Differences in the evolutionary rates were also found between different spatial arrangements. Thus, this study supports the hypothesis that population structure has indeed an influence on the rate of molecular evolution and especially on the neutral rate of evolution. Population structure Rate of molecular evolution Neutral evolution Forward population genetic simulations Dewey 590 Master en biologie, Option Biodiversité et Systématique (BDS) 44 Département de génétique et évolution 162 false 827 Groupe Montoya eba6a9c2-f245-405e-85c9-c4bf769d9ac8 Master thesis Restricted Master_E_B(1).pdf 11227554 application/pdf restrictedAccess Faculté des sciences / Section de biologie / Département de génétique et évolution

Title	Published in	Access level	OA Policy	Year	Views	Downloads

Influence of population structure on the rate of molecular evolution				2018	95	4

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Bizet, Elisabeth