Enhanced intimal thickening of expanded polytetrafluoroethylene grafts coated with fibrin or fibrin-releasing vascular endothelial growth factor in the pig carotid artery interposition model

Article Article scientifique Article Enhanced intimal thickening of expanded polytetrafluoroethylene grafts coated with fibrin or fibrin-releasing vascular endothelial growth factor in the pig carotid artery interposition model eng 2007 author Walpoth Beat 589195 author Zammaretti Schaer Prisca 601457 author Cikirikcioglu Mustafa 135609 author Khabiri Ebrahim 24085 author Djebaili Merzouk Karim 503958 author Pache Jean-Claude 513830 author Tille Jean-Christophe 87627 author Aggoun Yacine 562608 author Morel Denis 22755 author Kalangos Afksendiyos 132614 author Hubbell Jeffrey A author Zisch Andreas H 1163-1170 10.1016/j.jtcvs.2007.01.029 17467424 0022-5223 Intimal hyperplasia and surface thrombogenicity are major factors in the high failure rate of synthetic small-diameter bypass grafts. Vascular endothelial growth factor is a potent stimulus for endothelial growth, and its provision in a fibrin matrix coating at the luminal graft surface may hold a key to spontaneous graft endothelialization and improved graft patency. Animals Blood Vessel Prosthesis Blood Vessel Prosthesis Implantation Capillaries/pathology Carotid Arteries/pathology/surgery Coated Materials, Biocompatible Fibrin/pharmacology Graft Occlusion, Vascular/pathology Immunohistochemistry Macrophages/pathology Polytetrafluoroethylene Sus scrofa Tunica Intima/pathology Vascular Endothelial Growth Factor A/pharmacology Vascular Patency Dewey 616.07 Dewey 617 Dewey 618 137 Département de pathologie et immunologie 21F 57 Département de chirurgie 222 58 Département de pédiatrie, gynécologie et obstétrique 223 false 80 Chirurgie cardio-vasculaire 105 392 Groupe Pache Jean-Claude (pathologie clinique) 658 Journal of thoracic and cardiovascular surgery 133 5 7755c9ce-b762-4e18-a1e3-d02a614a59aa Article (Published version) Restricted 1-s2.0-S0022522307002176-main.pdf 1449914 application/pdf restrictedAccess Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie Faculté de médecine / Section de médecine clinique / Département de chirurgie Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique

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Enhanced intimal thickening of expanded polytetrafluoroethylene grafts coated with fibrin or fibrin-releasing vascular endothelial growth factor in the pig carotid artery interposition model	Journal of thoracic and cardiovascular surgery			2007	625	2

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Zammaretti Schaer, Prisca