Interdependence of filamentous actin and microtubules for asymmetric cell division

Article Article scientifique Article Interdependence of filamentous actin and microtubules for asymmetric cell division eng 2000 author Schaer Claudia 598082 author Riezman Howard 134430 815-825 10.1515/BC.2000.104 11076014 1431-6730 Asymmetric cell divisions are crucial to the generation of cell fate diversity. They contribute to unequal distribution of cellular factors to the daughter cells. Asymmetric divisions are characterized by a 90 degrees rotation of the mitotic spindle. There is increasing evidence that a tight cooperation between cortical, filamentous actin and astral microtubules is indispensable for successful spindle rotation. Over the past years, the dynactin complex has emerged as a key candidate to mediate actin/microtubule interaction at the cortex. This review discusses our current understanding of how spindle rotation is accomplished by the interplay of filamentous actin and microtubules in a variety of experimental systems. Ascidian embryos Asymmetric cell division Dynactin Pelvetia Saccharomyces cerevisiae Xenopus true Biological chemistry 381 9-10 b6aeac63-9d4f-41cb-8aec-3e4db391dd69 Article (Published version) Public C.Schaerer-Brodbeck.pdf 279908 application/pdf openAccess

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Interdependence of filamentous actin and microtubules for asymmetric cell division	Biological chemistry			2000	533	535

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Schaer, Claudia