Impact of Pulvinar Stroke on Attention Behaviour and Resting-State Connectivity

Diplôme Master Impact of Pulvinar Stroke on Attention Behaviour and Resting-State Connectivity eng 2021 author Angué Lauriane Yvette Huguette 582978 director Guedj Carole 0000-0001-9477-8873 861425 director Vuilleumier Patrik 0000-0002-8198-9214 134853 The recruitement of brain loci by selective attention has been well characterised at the cortical level, through the VAN and the DAN networks. However, recent research has highlighted the role of subcortical structures in attention. In particular the pulvinar, the most posterior thalamic nuclei, has been hypothetised to act in attention engagement, as a filter distractor, or as a coordinator synchronizing top-down and bottom-up cortical signals. Here, fMRI resting state brain activity of stroke patients with pulvinar lesion and a matching control population was recorded prior an attentional task. Partial correlation between VAN, DAN, Saliency networks were calculated by FSLNets, and matched to lesion parameters and behavioural measures. The selective attentional task was designed with two contradictory stimuli to modulate top-down and bottom-up signal processing. Task's RTs behavioural analysis completed the analysis and along with prospective resting-state, results are in support of a broader view of the pulvinar, as a key-player in the harmonisation of endogenous and exogenous processes. Attention Pulvinar Stroke Connectivity Dewey 616.8 Master en neurosciences 16 Centre interfacultaire de neurosciences 0D9 53 Département de neurosciences fondamentales 21A false 428 Mécanismes cérébraux du comportement et des fonctions cognitives 701 1d82a9b5-6d68-4303-8f47-59e410f1a75c Master thesis Restricted Master-thesis-LAngué.pdf 15845201 application/pdf restrictedAccess Centres et instituts / Centre interfacultaire de neurosciences Faculté de médecine / Section de médecine fondamentale / Département de neurosciences fondamentales

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Impact of Pulvinar Stroke on Attention Behaviour and Resting-State Connectivity				2021	106	7

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Angué, Lauriane Yvette Huguette