Induction of influenza-specific mucosal immunity by an attenuated recombinant Sendai virus

Article Article scientifique Article Induction of influenza-specific mucosal immunity by an attenuated recombinant Sendai virus eng 2011 author Le Thuc-vy L author Mironova Elena 508784 author Garcin Dominique 24296 author Compans Richard W e18780 10.1371/journal.pone.0018780 21533151 1932-6203 Many pathogens initiate infection at the mucosal surfaces; therefore, induction of mucosal immune responses is a first level of defense against infection and is the most powerful means of protection. Although intramuscular injection is widely used for vaccination and is effective at inducing circulating antibodies, it is less effective at inducing mucosal antibodies. Animals Antibodies, Viral/biosynthesis Genetic Vectors Genome, Viral Immunity, Mucosal Influenza A virus/immunology/isolation & purification Mice Orthomyxoviridae Infections/immunology/prevention & control/virology Recombination, Genetic Sendai virus/genetics/physiology Dewey 616 54 Département de microbiologie et médecine moléculaire 21B false 216 Virologie moléculaire 275 PloS one 6 4 73270723-1b1d-4f43-8997-ea241d678e6a Article (Published version) Public pone.0018780.pdf 1619790 application/pdf CC BY openAccess Faculté de médecine / Section de médecine fondamentale / Département de microbiologie et médecine moléculaire

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Induction of influenza-specific mucosal immunity by an attenuated recombinant Sendai virus	PloS one			2011	666	417

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