Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine’s rewarding effects but preserves natural reward processing

Article Article scientifique Article Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine’s rewarding effects but preserves natural reward processing eng 2021-10-22 author Andrianarivelo Njiva Andry 0000-0002-6369-4201 CNRS, UMR 8246, Neuroscience Paris Seine, F-75005 Paris, France. 416856 Département de neurosciences fondamentales (NEUFO) author Saint-Jour Estefani 0000-0002-0947-6801 CNRS, UMR 8246, Neuroscience Paris Seine, F-75005 Paris, France. author Pousinha Paula 0000-0002-5992-9418 Université Côte d’Azur, Nice, France, author Fernandez Sebastian P. Université Côte d’Azur, Nice, France, author Petitbon Anna Université Bordeaux, INRAE, Bordeaux INP, NutriNeuro, 33000 Bordeaux, France. author De Smedt-Peyrusse Veronique Université Bordeaux, INRAE, Bordeaux INP, NutriNeuro, 33000 Bordeaux, France. author Heck Nicolas 0000-0002-5754-8873 CNRS, UMR 8246, Neuroscience Paris Seine, F-75005 Paris, France. author Ortiz Vanesa 0000-0001-7250-0555 Université Côte d’Azur, Nice, France, author Allichon Marie-Charlotte CNRS, UMR 8246, Neuroscience Paris Seine, F-75005 Paris, France. author Kappès Vincent 0000-0001-6650-7937 CNRS, UMR 8246, Neuroscience Paris Seine, F-75005 Paris, France. author Betuing Sandrine 0000-0002-4733-6922 CNRS, UMR 8246, Neuroscience Paris Seine, F-75005 Paris, France. author Walle Roman 0000-0003-0718-2751 Université Bordeaux, INRAE, Bordeaux INP, NutriNeuro, 33000 Bordeaux, France. author Zhu Ying Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY 10032, USA. author Joséphine Charlène Commissariat à l’Énergie Atomique et aux Énergies Alternatives (CEA), Département de la Recherche Fondamentale, Institut de biologie François Jacob, MIRCen, and CNRS UMR 9199, Université Paris-Sud, Université Paris-Saclay, Neurodegenerative Diseases Laboratory, Fontenay-aux-Roses, France. author Bemelmans Alexis-Pierre 0000-0001-7605-5225 Commissariat à l’Énergie Atomique et aux Énergies Alternatives (CEA), Département de la Recherche Fondamentale, Institut de biologie François Jacob, MIRCen, and CNRS UMR 9199, Université Paris-Sud, Université Paris-Saclay, Neurodegenerative Diseases Laboratory, Fontenay-aux-Roses, France. author Turecki Gustavo 0000-0003-4075-2736 Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, QC, Canada. author Mechawar Naguib Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, QC, Canada. author Javitch Jonathan A. 0000-0001-7395-2967 Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY 10032, USA. author Caboche Jocelyne CNRS, UMR 8246, Neuroscience Paris Seine, F-75005 Paris, France. author Trifilieff Pierre 0000-0002-7893-9697 Université Bordeaux, INRAE, Bordeaux INP, NutriNeuro, 33000 Bordeaux, France. author Barik Jacques 0000-0002-4276-0927 Université Côte d’Azur, Nice, France, author Vanhoutte Peter 0000-0001-9236-4888 CNRS, UMR 8246, Neuroscience Paris Seine, F-75005 Paris, France. eabg5970 10.1126/sciadv.abg5970 34669474 2375-2548 PMC8528421 https://www.science.org/doi/10.1126/sciadv.abg5970 <p>D2R-NMDAR receptor heteromers are potential therapeutic targets in drug addiction.</p> true 973 Les dysfonctions synaptiques du cerveau 971 Science advances 7 43 e003b006-1200-4d14-8775-04796c277e66 Article (Published version) Public Article-scientifique-from-unpaywall.pdf 1226492 application/pdf CC BY-NC-4.0 dde1c9a7a6a22f54bdb271a9d77e8119d351a4aa97310230178794159290eb2d openAccess

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Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine’s rewarding effects but preserves natural reward processing	Science advances			2021	89	125

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