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Title

Insulin modulation of luteinizing hormone secretion in normal female volunteers and lean polycystic ovary syndrome patients

Authors
Stettler, Rodrigue
Waeber, Gérard
Wirthner, Daniel
Giusti, Vittorio
Tappy, Luc
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Published in Neuroendocrinology. 2009, vol. 89, no. 2, p. 131-9
Abstract Endocrine features of polycystic ovary syndrome (PCOS) include altered ovarian steroidogenesis, hyperinsulinemia and abnormal luteinizing hormone (LH) secretion. This study was undertaken to further evaluate the role of insulin to modulate LH secretion in lean PCOS patients with normal insulin sensitivity and normal volunteers.
Keywords AdultFemaleGlucose Clamp TechniqueGonadotropin-Releasing Hormone/metabolismHumansHypothalamus/metabolismInsulin/administration & dosage/blood/pharmacologyLuteinizing Hormone/blood/drug effects/secretionPolycystic Ovary Syndrome/metabolismThinness
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PMID: 18832802
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Research group Groupe Desmeules Jules (pharmacologie/toxicologie) (567)
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MORET BOCHATAY, Mallory et al. Insulin modulation of luteinizing hormone secretion in normal female volunteers and lean polycystic ovary syndrome patients. In: Neuroendocrinology, 2009, vol. 89, n° 2, p. 131-9. https://archive-ouverte.unige.ch/unige:99806

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Deposited on : 2017-11-29

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