en
Scientific article
English

Role of Gag mutations in PI resistance in the Swiss HIV cohort study: bystanders or contributors?

Published inJournal of Antimicrobial Chemotherapy, vol. 72, no. 3, p. 866-875
Publication date2017
Abstract

HIV Gag mutations have been reported to confer PI drug resistance. However, clinical implications are still controversial and most current genotyping algorithms consider solely the protease gene for assessing PI resistance.

Keywords
  • Cohort Studies
  • Drug Resistance
  • Viral/genetics
  • Genes
  • Gag
  • Genotype
  • HIV Infections/blood/drug therapy/virology
  • HIV Protease/genetics
  • HIV Protease Inhibitors/pharmacology/therapeutic use
  • HIV-1/drug effects/genetics
  • Humans
  • Mutation
  • Missense
  • Prevalence
  • RNA
  • Viral/blood
  • Sequence Analysis
  • DNA
  • Switzerland
  • Treatment Failure
  • Gag Gene Products
  • Human Immunodeficiency Virus/genetics
Citation (ISO format)
KLETENKOV, K et al. Role of Gag mutations in PI resistance in the Swiss HIV cohort study: bystanders or contributors? In: Journal of Antimicrobial Chemotherapy, 2017, vol. 72, n° 3, p. 866–875. doi: 10.1093/jac/dkw493
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0305-7453
451views
0downloads

Technical informations

Creation10/30/2017 11:03:00 AM
First validation10/30/2017 11:03:00 AM
Update time03/15/2023 2:30:14 AM
Status update03/15/2023 2:30:14 AM
Last indexation01/17/2024 1:37:29 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack