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Title

Antiretroviral-treated HIV-1 patients can harbour resistant viruses in CSF despite an undetectable viral load in plasma

Authors
Soulie, Cathia
Grudé, Maxime
Descamps, Diane
Amiel, Corinne
Morand-Joubert, Laurence
Raymond, Stéphanie
Pallier, Coralie
Bellecave, Pantxika
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Published in Journal of Antimicrobial Chemotherapy. 2017, vol. 72, no. 8, p. 2351-2354
Abstract HIV therapy reduces the CSF HIV RNA viral load (VL) and prevents disorders related to HIV encephalitis. However, these brain disorders may persist in some cases. A large population of antiretroviral-treated patients who had a VL > 1.7 log 10 copies/mL in CSF with detectable or undetectable VL in plasma associated with cognitive impairment was studied, in order to characterize discriminatory factors of these two patient populations.
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PMID: 28472307
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SOULIE, Cathia et al. Antiretroviral-treated HIV-1 patients can harbour resistant viruses in CSF despite an undetectable viral load in plasma. In: Journal of Antimicrobial Chemotherapy, 2017, vol. 72, n° 8, p. 2351-2354. https://archive-ouverte.unige.ch/unige:99801

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Deposited on : 2017-11-29

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