UNIGE document Scientific Article
previous document  unige:99523  next document
add to browser collection
Title

Appropriate endpoints for evaluation of new antibiotic therapies for severe infections: a perspective from COMBACTE's STAT-Net

Authors
Timsit, Jean-François
de Kraker, Marlieke E A
Sommer, Harriet
Weiss, Emmanuel
Bettiol, Esther
Wolkewitz, Martin
Nikolakopoulos, Stavros
Wilson, David
show hidden authors show all authors [1 - 9]
Published in Intensive Care Medicine. 2017, vol. 43, no. 7, p. 1002-1012
Abstract In this era of rising antimicrobial resistance, slowly refilling antibiotic development pipelines, and an aging population, we need to ensure that randomized clinical trials (RCTs) determine the added benefit of new antibiotic agents effectively and in a valid way, especially for severely ill patients. Unfortunately, universally accepted endpoints for the evaluation of new drugs in severe infections are lacking.
Identifiers
PMID: 28466147
Full text
Article (Published version) (1 MB) - public document Free access
Structures
Research group Groupe Harbarth Stephan (Staphylocoques dorés résistants à la méthicilline) (866)
Citation
(ISO format)
TIMSIT, Jean-François et al. Appropriate endpoints for evaluation of new antibiotic therapies for severe infections: a perspective from COMBACTE's STAT-Net. In: Intensive Care Medicine, 2017, vol. 43, n° 7, p. 1002-1012. https://archive-ouverte.unige.ch/unige:99523

83 hits

27 downloads

Update

Deposited on : 2017-11-22

Export document
Format :
Citation style :