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Title

Low pre-treatment B-cell counts are not a risk factor of infection in patients treated with rituximab for autoimmune diseases: An observational study

Authors
Gascon, Danielle
Published in Joint, Bone, Spine. 2016, vol. 83, no. 2, p. 191-7
Abstract Rituximab (RTX) is increasingly used in patients with refractory rheumatoid arthritis (RA) and other severe autoimmune diseases (AID). In practice, many clinicians are reluctant to prescribe RTX in patients with low B-cell counts because of the presumed risk of infection. The aim of this study was therefore to investigate whether B-cell counts before treatment or retreatment with RTX predict the occurrence of infections.
Keywords AdultAged80 and overAutoimmune Diseases/drug therapy/immunologyB-Lymphocytes/immunologyFemaleHumansImmunologic Factors/adverse effects/immunology/therapeutic useInfection/chemically induced/etiology/immunologyLymphocyte CountMaleMiddle AgedRisk FactorsRituximab/adverse effects/immunology/therapeutic useYoung Adult
Identifiers
PMID: 26677998
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Structures
Research groups Groupe Seebach Jorg Dieter (transplantation et immunologie) (856)
Mécanisme de l'inflammation articulaire (44)
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(ISO format)
LAZAROU, Ilias et al. Low pre-treatment B-cell counts are not a risk factor of infection in patients treated with rituximab for autoimmune diseases: An observational study. In: Joint, Bone, Spine, 2016, vol. 83, n° 2, p. 191-7. https://archive-ouverte.unige.ch/unige:99469

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Deposited on : 2017-11-22

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