Scientific article
English

Genistein, a protein tyrosine kinase inhibitor, ameliorates retinal degeneration after ischemia-reperfusion injury in rat

Published inInvestigative Ophthalmology & Visual Science, vol. 38, no. 6, p. 1193-1202
Publication date1997
Abstract

The authors sought to determine the effect of genistein, a naturally occurring protein tyrosine kinase inhibitor, in a model of ischemia-reperfusion injury in the rat retina.

Keywords
  • Animals
  • Enzyme Inhibitors/pharmacology
  • Eye Proteins/metabolism
  • Genistein
  • Ischemia/pathology/prevention & control
  • Isoflavones/pharmacology
  • Male
  • Phosphorylation
  • Protein-Tyrosine Kinases/antagonists & inhibitors
  • Rats
  • Rats, Sprague-Dawley
  • Reperfusion Injury/pathology/prevention & control
  • Retina/drug effects/metabolism/pathology
  • Retinal Degeneration/etiology
  • Retinal Vessels/drug effects
  • Tyrosine/metabolism
Affiliation entities Not a UNIGE publication
Citation (ISO format)
HAYASHI, A et al. Genistein, a protein tyrosine kinase inhibitor, ameliorates retinal degeneration after ischemia-reperfusion injury in rat. In: Investigative Ophthalmology & Visual Science, 1997, vol. 38, n° 6, p. 1193–1202.
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN0146-0404
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