Multipotent mesenchymal stromal cells enhance insulin secretion from human islets via N-cadherin interaction and prolong function of transplanted encapsulated islets in mice

Montanari, Elisa; Meier, Raphaël; Mahou, Redouan; Seebach, Jorg Dieter; Wandrey, Christine; Gerber-Lemaire, Sandrine; Buehler, Leo Hans; Gonelle-Gispert, Carmen

doi:10.1186/s13287-017-0646-7

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Title		Multipotent mesenchymal stromal cells enhance insulin secretion from human islets via N-cadherin interaction and prolong function of transplanted encapsulated islets in mice
Authors		Montanari, Elisa Meier, Raphaël Mahou, Redouan Seebach, Jorg Dieter Wandrey, Christine Gerber-Lemaire, Sandrine Buehler, Leo Hans Gonelle-Gispert, Carmen
Published in		Stem cell research & therapy. 2017, vol. 8, no. 1, 199
Abstract		Multipotent mesenchymal stromal cells (MSC) enhance viability and function of islets of Langerhans. We aimed to examine the interactions between human MSC and human islets of Langerhans that influence the function of islets.
Keywords		Cell interaction — Encapsulation — Human islets — Mesenchymal stromal cells — N-cadherin
Identifiers		DOI: 10.1186/s13287-017-0646-7 PMID: 28962589
Full text		Article (Published version) (6.6 MB) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine clinique / Département de chirurgie
Research groups		Chirurgie viscérale (104) Chirurgie viscérale (HUG) Laboratoire d'immunologie translationnelle (856) Transplantation et hépatologie (905)
Citation (ISO format)		MONTANARI, Elisa et al. Multipotent mesenchymal stromal cells enhance insulin secretion from human islets via N-cadherin interaction and prolong function of transplanted encapsulated islets in mice. In: Stem Cell Research and Therapy, 2017, vol. 8, n° 1, p. 199. doi: 10.1186/s13287-017-0646-7 https://archive-ouverte.unige.ch/unige:99002