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Titles listHuman anti-pig NK cell and CD8(+) T-cell responses in the presence of regulatory dendritic cells
Titles listHuman anti-pig NK cell and CD8(+) T-cell responses in the presence of regulatory dendritic cells
Scientific Article
unige:98887 
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Human anti-pig NK cell and CD8(+) T-cell responses in the presence of regulatory dendritic cells |
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| Published in | Xenotransplantation. 2016, vol. 23, no. 6, p. 479-489 | |
| Abstract | Dendritic cells (DC) play a major role in natural killer (NK) cell and cytotoxic T lymphocyte (CTL) activation leading to cell-mediated xenogeneic responses. In contrast, the use of in vitro differentiated regulatory DC may represent an attractive approach to protect porcine endothelial cells (pEC) from human cell-mediated immune responses. In this study, we evaluated the potential of human regulatory DC to reduce xenogeneic NK cell and CTL responses to pEC. | |
| Identifiers | DOI: 10.1111/xen.12279 PMID: 27862343 | |
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| Research group | Groupe Seebach Jorg Dieter (transplantation et immunologie) (856) | |
| Citation (ISO format) | MADELON, Natacha, PUGA YUNG, Gisella, SEEBACH, Jorg Dieter. Human anti-pig NK cell and CD8(+) T-cell responses in the presence of regulatory dendritic cells. In: Xenotransplantation, 2016, vol. 23, n° 6, p. 479-489. https://archive-ouverte.unige.ch/unige:98887 |
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