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Avoiding Pitfalls in the Interpretation of Gadoxetic Acid-Enhanced Magnetic Resonance Imaging

Dioguardi Burgio, Marco
Vilgrain, Valérie
Brancatelli, Giuseppe
Published in Seminars in Ultrasound Ct and Mri. 2016, vol. 37, no. 6, p. 561-572
Abstract Gadoxetic acid is extensively used in the following 3 main clinical situations: characterization of small nodules in patients with cirrhosis, preoperative staging of liver metastases, and characterization of incidentally discovered focal liver lesions. Owing to the rapid entry of gadoxetic acid into hepatocytes, the traditional features of liver tumors are modified on magnetic resonance (MR) imaging, especially during delayed phase sequences. Thus, although the added value of gadoxetic acid for the detection and characterization of focal liver lesions is now clear, its unique pharmacokinetics as well as the presence of mimicking and atypical lesions may lead to misdiagnoses. The goal of this article is to illustrate common and uncommon pitfalls associated with the use of gadoxetic acid-enhanced MR imaging. Moreover, additional MR imaging features that can help establish a correct diagnosis are described.
Keywords Contrast MediaGadolinium DTPAHumansImage Interpretation, Computer-Assisted/methodsLiver Diseases/diagnostic imagingMagnetic Resonance Imaging/methodsSensitivity and Specificity
PMID: 27986174
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Research group Imagerie per-opératoire multi-modalité en radiologie interventionnelle (949)
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DIOGUARDI BURGIO, Marco et al. Avoiding Pitfalls in the Interpretation of Gadoxetic Acid-Enhanced Magnetic Resonance Imaging. In: Seminars in Ultrasound Ct and Mri, 2016, vol. 37, n° 6, p. 561-572. doi: 10.1053/j.sult.2016.08.002 https://archive-ouverte.unige.ch/unige:98782

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Deposited on : 2017-11-08

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