Multimodal imaging Gd-nanoparticles functionalized with Pittsburgh compound B or a nanobody for amyloid plaques targeting

Pansieri, Jonathan; Plissonneau, Marie; Stransky-Heilkron, Nathalie Martine; Dumoulin, Mireille; Heinrich-Balard, Laurence; Rivory, Pascaline; Morfin, Jean-François; Toth, Eva; Saraiva, Maria Joao; Allémann, Eric; Tillement, Olivier; Forge, Vincent; Lux, François; Marquette, Christel

doi:10.2217/nnm-2017-0079

Scientific article

English

Multimodal imaging Gd-nanoparticles functionalized with Pittsburgh compound B or a nanobody for amyloid plaques targeting

ContributorsPansieri, Jonathan; Plissonneau, Marie; Stransky-Heilkron, Nathalie Martine; Dumoulin, Mireille; Heinrich-Balard, Laurence; Rivory, Pascaline; Morfin, Jean-François; Toth, Eva; Saraiva, Maria Joao; Allémann, Eric; Tillement, Olivier; Forge, Vincent; Lux, François; Marquette, Christel

Published inNanomedicine, vol. 12, no. 14, p. 1675-1687

Publication date2017

Abstract

Gadolinium-based nanoparticles were functionalized with either the Pittsburgh compound B or a nanobody (B10AP) in order to create multimodal tools for an early diagnosis of amyloidoses.

Affiliation

Faculté des sciences / Section des sciences pharmaceutiques

Research group

Technologie pharmaceutique

Citation (ISO format)

PANSIERI, Jonathan et al. Multimodal imaging Gd-nanoparticles functionalized with Pittsburgh compound B or a nanobody for amyloid plaques targeting. In: Nanomedicine, 2017, vol. 12, n° 14, p. 1675–1687. doi: 10.2217/nnm-2017-0079

Article (Published version)

Identifiers

PID : unige:98724
DOI : 10.2217/nnm-2017-0079
PMID : 28635419

ISSN of the journal1549-9634

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First validation09/22/2017 10:30:00 AM

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Multimodal imaging Gd-nanoparticles functionalized with Pittsburgh compound B or a nanobody for amyloid plaques targeting

Gadolinium-based nanoparticles were functionalized with either the Pittsburgh compound B or a nanobody (B10AP) in order to create multimodal tools for an early diagnosis of amyloidoses.

Technical informations