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Title

Improved Survival in a Long-Term Rat Model of Sepsis Is Associated With Reduced Mitochondrial Calcium Uptake Despite Increased Energetic Demand

Authors
Dyson, Alex
Umbrello, Michele
Carré, Jane E
Ritter, Cristiane
Clatworthy, Innes
Duchen, Michael R
Singer, Mervyn
Published in Critical Care Medicine. 2017, vol. 45, no. 8, p. e840-e848
Abstract To investigate the relationship between prognosis, changes in mitochondrial calcium uptake, and bioenergetic status in the heart during sepsis.
Keywords AnimalsCalcium/metabolismDobutamine/pharmacologyEchocardiographyMaleMicroscopy ElectronMitochondria/metabolismMyocytes Cardiac/metabolismNAD/metabolismRatsRats WistarSarcoplasmic Reticulum/metabolismSepsis/physiopathology
Identifiers
PMID: 28410346
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Article (Published version) (1.6 MB) - document accessible for UNIGE members only Limited access to UNIGE
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Research group Groupe de recherche en hémodynamique (913)
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BOLLEN PINTO, Bernardo et al. Improved Survival in a Long-Term Rat Model of Sepsis Is Associated With Reduced Mitochondrial Calcium Uptake Despite Increased Energetic Demand. In: Critical Care Medicine, 2017, vol. 45, n° 8, p. e840-e848. https://archive-ouverte.unige.ch/unige:98625

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Deposited on : 2017-11-07

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