UNIGE document Scientific Article
previous document  unige:9862  next document
add to browser collection
Title

The Ace locus of Drosophila melanogaster: structural gene for acetylcholinesterase with an unusual 5' leader

Authors
Hall, Lucinda M. C.
Published in EMBO Journal. 1986, vol. 5, no. 11, p. 2949-54
Abstract The Ace locus of Drosophila melanogaster has been mapped at the molecular level. cDNA clones from the locus have been isolated and their sequence determined, confirming that Ace forms the structural gene for acetylcholinesterase (AChE). The cDNAs have a 1950 nucleotide open reading frame from which the complete amino acid sequence of AChE has been deduced. The Drosophila enzyme is found to have extensive homology to the known sequence of Torpedo AChE. Ace cDNAs have an unusual structure with a long 5' leader and several short upstream open reading frames.
Keywords Acetylcholinesterase/geneticsAmino Acid SequenceAnimalsBase SequenceDNA Restriction EnzymesDrosophila melanogaster/enzymology/geneticsGenesProtein Sorting Signals/analysisTranscription, Genetic
Identifiers
PMID: 3024971
Full text
Article (Published version) (1.3 MB) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Citation
(ISO format)
HALL, Lucinda M. C., SPIERER, Pierre. The Ace locus of Drosophila melanogaster: structural gene for acetylcholinesterase with an unusual 5' leader. In: EMBO Journal, 1986, vol. 5, n° 11, p. 2949-54. https://archive-ouverte.unige.ch/unige:9862

140 hits

0 download

Update

Deposited on : 2010-08-06

Export document
Format :
Citation style :