en
Scientific article
English

A gene required for the specification of dorsal-ventral pattern in Drosophila appears to encode a serine protease

Published inNature, vol. 323, no. 6090, p. 688-692
Publication date1986
Abstract

The maternal effect gene snake is required for the establishment of the dorsal-ventral axis during the embryonic development of Drosophila. The molecular cloning of the gene and analysis of a complementary DNA sequence suggest that the gene encodes a serine protease which is structurally similar to proteases involved in blood clotting, peptide processing, and complement fixation pathways.

Keywords
  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Drosophila melanogaster/genetics/growth & development
  • Female
  • Genes, Insect
  • Molecular Sequence Data
  • Serine Endopeptidases/isolation & purification/physiology
  • Transcription Factors/isolation & purification/physiology
Citation (ISO format)
DELOTTO, Robert, SPIERER, Pierre. A gene required for the specification of dorsal-ventral pattern in <i>Drosophila</i> appears to encode a serine protease. In: Nature, 1986, vol. 323, n° 6090, p. 688–692. doi: 10.1038/323688a0
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Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0028-0836
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