GPR40 mediates potential positive effects of a saturated fatty acid enriched diet on bone

Philippe, Claire; Wauquier, Fabien; Landrier, Jean-François; Bonnet, Lauriane; Miot-Noirault, Elisabeth; Rochefort, Gaël Y; Sadoine, Jérémy; Asrih, Mohamed; Jornayvaz, François; Bernalier, Annick; Coxam, Véronique; Wittrant, Yohann

doi:10.1002/mnfr.201600219

Scientific article

English

GPR40 mediates potential positive effects of a saturated fatty acid enriched diet on bone

ContributorsPhilippe, Claire; Wauquier, Fabien; Landrier, Jean-François; Bonnet, Lauriane; Miot-Noirault, Elisabeth; Rochefort, Gaël Y; Sadoine, Jérémy; Asrih, Mohamed; Jornayvaz, François

; Bernalier, Annick; Coxam, Véronique; Wittrant, Yohann

Published inMolecular Nutrition and Food Research, vol. 61, no. 2

Publication date2017

Abstract

The stimulation of the free fatty acid receptor G-protein coupled receptor (GPR) 40 by GW9508 prevents bone loss by inhibiting osteoclast activity, both in vitro and in vivo. Here, we questioned whether the stimulation of the GPR40 receptor by dietary fatty acids may lead to the same beneficial effect on bone.

Affiliation entities

Not a UNIGE publication

Citation (ISO format)

PHILIPPE, Claire et al. GPR40 mediates potential positive effects of a saturated fatty acid enriched diet on bone. In: Molecular Nutrition and Food Research, 2017, vol. 61, n° 2. doi: 10.1002/mnfr.201600219

Article (Published version)

Identifiers

PID : unige:98426
DOI : 10.1002/mnfr.201600219
PMID : 27611773

Journal ISSN1613-4125

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Creation28/07/2017 09:51:00

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Update15/03/2023 02:14:55

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GPR40 mediates potential positive effects of a saturated fatty acid enriched diet on bone

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